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Cellular Immunologist Consultant (Contract)

Pantalent

United Kingdom

Remote

GBP 80,000 - 100,000

Part time

Yesterday
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Job summary

A leading life sciences company in the UK is looking for an experienced Cellular Immunologist Consultant to provide expert scientific guidance for their cutting-edge cancer therapy projects. The ideal candidate will have a Ph.D. and over 8 years of research experience in cellular immunology and cancer immunotherapy. This role offers the opportunity to significantly impact the development of innovative cancer treatments in a rapidly growing field. Flexible and remote working options are available.

Qualifications

  • Minimum of 8 years of hands-on research experience in cellular immunology.
  • Proven track record of designing and interpreting complex immunological experiments.
  • Extensive expertise in multi-parameter flow cytometry.

Responsibilities

  • Provide expert consultation on scientific strategies for cell therapy programs.
  • Guide the development and validation of immunology-focused assays.
  • Analyze and interpret complex immunological data from preclinical studies.

Skills

Deep immunological expertise
Problem-solving & analytical
Communication
Strategic thinking
Independence & flexibility

Education

Ph.D. in Immunology, Cellular Biology, Cancer Biology

Tools

FlowJo
FCS Express

Job description

Location: Flexible/Remote

Company: Longevity Labs (part of Great Good Venture Studio)

Engagement Type: Contract / Freelance

About Great Good

Great Good is a pioneering venture studio at the intersection of biotech and AI. We launch transformative therapeutic projects by providing initial investment, world-class teams, and state-of-the-art infrastructure. Our model empowers visionary leaders to accelerate drug development and harness AI-driven innovation to address unmet medical needs. Benefits of Working with Great Good Venture Studio

  • Accelerated Development:

Our venture studio model streamlines the typically lengthy process of biotech innovation. With access to expert operational, legal, finance, and HR teams, you can bypass common startup hurdles and focus immediately on scientific advancement and strategic growth.

  • Integrated Resource Access:

You will have direct access to state-of-the-art labs, cutting-edge infrastructure, and specialized development and product teams tailored to your project’s unique needs—facilitating rapid iteration and optimized drug development pipelines.

  • Collaborative Synergies:

Joining our venture studio connects you with a vibrant ecosystem of experienced entrepreneurs, distinguished scientists, and industry leaders. This collaborative environment encourages cross-pollination of ideas, mentoring opportunities, and strategic partnerships, enhancing both innovation and your professional growth.

  • Strategic Support and Investment:

Beyond initial capital, Great Good provides ongoing strategic guidance and operational support. Our comprehensive back-office resources help manage day-to-day complexities while our investment in your venture ensures you have the means to scale quickly and capture market opportunities.

  • Enhanced Commercial Potential:

By working under the venture studio umbrella, you not only drive scientific breakthroughs but also elevate the commercial viability of your project. Our model is designed to maximize innovation in drug therapeutics and generate significant market value, positioning your venture for long-term success and impactful industry leadership.

About Longevity Labs

We are a diversified life sciences company with a strong interest in oncology, cell, and gene therapy spaces. One project under consideration is an autologous Dendritic Cell (DC), therapy for solid tumors. While DC therapies are regarded as safe, they have not achieved a high level of clinical benefit in patients. Low cell dose numbers and activation states, suboptimal routes of administration, and limited antigen range are all obstacles that our DC technology has demonstrated its ability to overcome in preclinical testing. The core technology has FDA approval for Phase I trials but needs optimization on the scale manufacturing and antigen production areas.

The Opportunity

We are seeking an experienced Cellular Immunologist Consultant to provide expert scientific guidance and hands-on support for our R&D team. As we rapidly advance our novel cell therapy program for oncology, your deep expertise in immunology, T-cell biology, and cancer immunotherapy will be critical in guiding our experimental design, data interpretation, and strategic decision-making. This is a unique opportunity to directly impact the development of groundbreaking cancer therapies in a fast-growing space.

Key Responsibilities

  • Scientific strategy & experimental design: provide expert consultation on the scientific strategy for our cell therapy programs, including target selection, cell engineering approaches, and preclinical optimization pathways. Advise on the design of in vitro and in vivo experiments to evaluate cell therapy efficacy, persistence, safety, and mechanism of action.
  • Assay development & optimization: Provide guidance on the development, optimization, and validation of immunology-focused assays relevant to cell therapy, including:

    • Multi-parameter flow cytometry for immunophenotyping and functional analysis.
    • Cytotoxicity assays (e.g., LDH cytotoxicity, impedance, luminescence).
    • Cytokine/chemokine profiling (e.g., ELISA, Luminex, MSD).
    • T-cell activation, proliferation, and differentiation assays.
    • Ex vivo analysis of tumor microenvironment and immune infiltrate.
  • Data analysis & interpretation: Critically analyze and interpret complex immunological data generated from preclinical studies. Provide insightful feedback to the research team, identify key findings, and troubleshoot experimental challenges.

  • Translational immunology: advise on translational strategies to bridge preclinical findings to clinical development, including biomarker identification and pharmacodynamic assessments.

  • Troubleshooting & problem solving: Provide expert insights and recommendations to overcome scientific hurdles and optimize our cell therapy constructs and manufacturing processes from an immunological perspective.

  • Literature & competitive review: Stay abreast of the latest advancements in cellular immunotherapy, cancer immunology, and relevant competitor pipelines. Provide critical reviews of scientific literature and competitive landscapes.

  • Reporting & presentation: Contribute to the preparation of scientific reports, presentations, and grant applications, ensuring scientific rigor and clarity. Present findings and recommendations to the leadership team and scientific advisory board.

  • Intellectual property input: Provide immunological insights to support the development of our intellectual property strategy.

Qualifications

  • Education: Ph.D. in Immunology, Cellular Biology, Cancer Biology, or a closely related field.Experience:
    • Minimum of 8 years of hands-on research experience in cellular immunology, with a significant focus on cancer immunotherapy and/or cell therapy development (e.g., CAR-T, TCR-T, NK cells), gained in an academic, biotech, or pharmaceutical setting.
    • Proven track record of designing, executing, and interpreting complex immunological experiments, both in vitro and in relevant in vivo models (e.g., syngeneic, xenograft).

    • Extensive expertise in multi-parameter flow cytometry and analysis using software like FlowJo or FCS Express.

    • Demonstrated understanding of cell therapy manufacturing principles and their impact on cell product quality and function is highly desirable.

    • Previous experience as a consultant or in a senior scientific advisory role to a biotech startup is a strong plus.

    • A strong publication record in top-tier immunology or cancer journals is highly valued.

Skills:

  • Deep immunological expertise: profound knowledge of Dendritic cell biology, T-cell signaling, tumor immunology, immune suppression mechanisms, and adoptive cell therapy principles.
  • Problem-solving & analytical: exceptional analytical skills with the ability to critically evaluate experimental designs, troubleshoot complex scientific issues, and derive meaningful conclusions from data.

  • Communication: excellent written and verbal communication skills, with the ability to clearly articulate complex scientific concepts to both scientific and non-scientific audiences.

  • Strategic thinking: ability to provide high-level strategic guidance and translate scientific insights into actionable development plans.

  • Independence & flexibility: proven ability to work independently, manage time effectively, and adapt to the dynamic needs of a fast-paced startup environment.

To Apply:

Interested candidates should submit a detailed resume/CV and a cover letter outlining their relevant expertise, experience in cell therapy/cancer immunology, and your proposed hourly or project-based consulting rate via the application form. Please also indicate your availability and preferred engagement model.

Application Link: https://forms.gle/hhSS9uVqLzNWxWxo6

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