Cell Culture Scientist

JR United Kingdom; Cambridge; On-site; GBP 33,000 - 40,000; Full time

Job summary

An established industry player is seeking a dedicated Cell Culture Scientist to join its innovative team in neuroscience drug discovery. This role offers a unique opportunity to work with human iPSCs, focusing on the production and differentiation of cell types crucial for neurological research. You will collaborate with project leaders to develop and execute cell-based assays while ensuring high-quality standards through rigorous quality control assessments. With a commitment to employee wellbeing, the company promotes a healthy work-life balance and offers a range of benefits, including a 4.5-day work week and private medical insurance. If you are passionate about making a difference in the field of neuroscience, this position is perfect for you.

Benefits

4.5-day work week

Employee Share Option Scheme

Non-contributory Life Assurance

BUPA Private Medical Insurance

Cycle-purchase scheme

Qualifications

• Honours degree in biological or physical sciences is essential.
• Advanced cell culture skills and hands-on expertise in relevant fields.

Responsibilities

• Maintain human iPSC lines and generate different cell types.
• Undertake quality control on iPSC lines and maintain QC data records.

Skills

Advanced Cell Culture Skills

Molecular Biology

Cell Biology

Biochemistry

Neuroscience Research

Gene Editing (CRISPR-Cas9)

Education

Honours Degree in Biological or Physical Sciences

Masters or PhD in Relevant Field

Job description

Cell Culture Scientist - Neurology Preclinical Drug Discovery Research

Talisman Therapeutics Ltd is a neuroscience drug discovery company based in Cambridge, UK. Building upon the world-class knowledge and skills of its team, Talisman develops and employs proprietary human stem cell models of neurodegenerative and neurological disease to advance the development of novel therapeutics through our internal research projects and external collaborations. This is an exciting time to join the company as we develop and expand our research portfolio.

We are currently recruiting a Cell Culture Scientist to join our well-established human cell culture team. This is an opportunity for an experienced and skilled cell culture scientist to join a specialist team working in the cell and molecular biology of neurological and neurodevelopmental diseases, including neurodegeneration and neuroinflammation. The ideal candidate will demonstrate enthusiasm for and commitment to cell culture research, combined with excellent organisational skills. Day-to-day tasks include management of cell type production from human iPSCs, undertaking detailed quality control assessments and working closely with the wider research team to support project delivery. We are looking for a collaborative team member who wants to make a difference as part of an experienced group.

Note that this role will require occasional weekend work based on a rota system.

Key Areas of Responsibility:

1. Human iPSC Culture and Differentiation
   • Responsibility for maintaining human iPSC lines
   • Generation of different cell types from human iPSCs, including neurons and microglia, to meet project needs
   • Supporting project leaders with development and execution of cell-based assays
2. Quality Control
   • Undertaking QC on iPSC lines
   • Maintenance of QC data records and reporting
   • Oversight of all QC on differentiated cells

Skills and Qualifications:

An honours degree in the biological or physical sciences is essential and a Masters or PhD in a relevant field (or equivalent experience) is desirable. Essential skills include advanced cell culture skills and hands-on expertise in at least one of: molecular/cell biology, biochemistry, chemistry or neuroscience research. Experience in working with stem cell models, complex coculture systems, organoids or gene editing approaches (e.g. CRISPR-Cas9) would be an advantage.

Employee Benefits:

The role will be based at the Babraham Research Campus, Cambridge. We offer excellent compensation and benefits that reflect the strong company commitment to employee wellbeing. Our benefits include a 4.5-day week for all staff to enable work-life balance, an Employee Share Option Scheme, a non-contributory Life Assurance scheme, non-contributory BUPA Private Medical Insurance and access to a cycle-purchase scheme. Salary will be in the region of £33,000-£40,000 depending on experience. Should you wish to be considered for this position, please send a CV via LinkedIn by Friday 9th May 2025 at 12:00 noon.