Biophysical Scientist

ZipRecruiter; London; On-site; GBP 40,000 - 60,000; Full time

Job summary

A biotech company is seeking a Biophysical Scientist in London to drive innovative experiments in DNA synthesis. Candidates should have proven wet lab expertise, experience with design of experiments, and the ability to work independently. This role offers collaborative team efforts, flexible hours, and a competitive salary. Join us in advancing DNA synthesis technology.

Benefits

Flexible working hours

Creative freedom

Competitive salary and benefits

Qualifications

• Hands-on expertise with experimental techniques and instrumentation.
• Results-driven design of experiments (DOE).
• Comfortable driving scientific processes independently.

Responsibilities

• Lead and execute cell-free DNA synthesis experiments.
• Design and optimize experiments using DOE methodologies.
• Contribute to grant writing supporting technical sections.

Skills

Wet lab expertise

Experimental design using DOE

Grant writing

Independent scientific processes

Agile and curious personality

Tools

Fluorescence spectroscopy

Cell culture techniques

ELISA assays

Job description

Job Description

Location

Euston, London UK

About Us

AmpliSynth is developing SynthBox, a modular, open-source DNA printer that enables same-day DNA synthesis without the bottlenecks of traditional supply chains. Our mission is to democratize access to

custom DNA and accelerate breakthroughs in biotechnology.

The Position

We are looking for a Biophysical Scientist to join our team, drive experimental innovation, and bridge gaps between biology, engineering, and automation.

Key Responsibilities

• Lead and execute cell-free DNA synthesisexperiments from concept to validation.

• Design and optimize experiments usingDesign of Experiments (DOE)methodologies to produce actionable results.

• Contribute to the grant writing process,supporting technical sections andexperimental justifications.

• Collaborate closely with hardware engineersto integrate biological workflows intoautomated systems.

• Proactively identify challenges, proposesolutions, and drive scientific processes with minimal oversight.

• Maintain detailed experimentaldocumentation and contribute to projectreporting for internal and externalstakeholders.

Essential Requirements

• Proven, hands-on wet lab expertise with standard and advanced experimental techniques and instrumentation

• Demonstrated use of results-driven DOE in experimental design.

• Familiarity with the grant writing process for research funding.

• Comfortable owning and driving scientific processes independently.

• Agile and curious personality

Nice to Have

• Hands-on expertise across multiple DNA synthesis techniques, both enzymatic (e.g., Gibson Assembly, Rolling Circle Amplification) and chemical (e.g., phosphoramidite chemistry).

• Experience with RNA synthesis workflows.

• Exposure to integrating hardware and biology (automation, robotics, lab • instrumentation).

• Experience with fluorescence spectroscopy

• Experience with cell culture techniques and ELISA assays.

• A proven track record of self-driven, end-to-end scientific projects.

Why Join Us?

• Contribute to meaningful projects that will make the world a better place

• Work in a collaborative, diverse, and international team

• Flexible working hours and great creative freedom.

• Opportunity to be at the forefront of next- DNA synthesis technology.

• Competitive Salary and Benefits (Pension, Bonus, etc)

How to Apply

Please send your CV and a short note explaining your relevant experience to [e-mail], before the 15th September 2025. For any further information, message [e-mail]