Biologics Discovery Scientist – In Vitro Display

AstraZeneca; Cambridge; On-site; GBP 60,000 - 80,000; Full time

Job summary

AstraZeneca in Cambridge is seeking a Research Scientist, Biologics Discovery – In Vitro Display to advance our therapeutic discovery pipeline. You will design and execute experiments across phage, yeast, mRNA, and ribosome display platforms to identify and optimise peptide and antibody candidates.

You will analyse data, apply experimental strategies, and communicate findings clearly within multidisciplinary teams.

Qualifications

• Experience with biologics hit identification and engineering using display technologies (phage, yeast, mRNA, ribosome).
• Molecular biology methods including PCR, cloning, Sanger sequencing.
• Automation to improve discovery efficiency and throughput.
• Awareness of AI/ML methods in therapeutic discovery for hit finding and lead optimisation.

Responsibilities

• Design and execute experiments across display platforms (phage, yeast, mRNA, ribosome).
• Analyze data, interpret results, and communicate findings to project teams.
• Collaborate with Biologics Engineering and cross-functional groups to address discovery challenges.

Skills

Phage display

Yeast display

mRNA display

Ribosome display

Molecular biology

PCR cloning

Automation

AI/ML in discovery

Data interpretation

Record keeping

Team collaboration

Troubleshooting

Education

Graduate level scientist

Job description

AstraZeneca in Cambridge is seeking a Research Scientist, Biologics Discovery – In Vitro Display to advance our therapeutic discovery pipeline. You will design and execute experiments across phage, yeast, mRNA, and ribosome display platforms to identify and optimise peptide and antibody candidates.

You will analyse data, apply experimental strategies, and communicate findings clearly within multidisciplinary teams.