Associate Scientist - CRISPR

JR United Kingdom; Oxford; On-site; GBP 30,000 - 45,000; Full time

Job summary

A leading biotech company in Oxford is looking for an Associate Scientist to advance mammalian cell line development. This role involves hands-on experimentation with CHO cell cultures and CRISPR gene editing, coupled with opportunities for innovative research in biologics.

Qualifications

• 3+ years of experience in a biotech environment or 1+ years with a PhD.
• Strong experience with CHO suspension cells.
• Comfortable in fast-paced lab environments.

Responsibilities

• Designing and executing CHO cell culture experiments.
• Running CRISPR knockout screens and transfections.
• Writing SOPs and maintaining lab documentation.

Skills

CHO cell culture

CRISPR/Cas9 techniques

FACS-based cell sorting

Experimental planning

Scientific communication

Education

BSc/MSc in biotech or pharma

PhD in relevant field

Tools

BD FACSAria Fusion

Beacon

Ambr15

Job description

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Associate Scientist - CRISPR, oxford district

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Client:

Cranleigh STEM, Sustainability & SHEQ Recruitment

Location:

oxford district, United Kingdom

Job Category:

Other

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EU work permit required:

Yes

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Job Views:

5

Posted:

31.05.2025

Expiry Date:

15.07.2025

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Job Description:

Associate Scientist – Target Discovery | Biotech | CHO Cell Lines | CRISPR

Location: Oxford

We’re hiring an Associate Scientist to join an innovative biotech team focused on advancing mammalian cell line development. If you're experienced in CHO cell culture and CRISPR gene-editing, and you're passionate about target discovery, this could be your next move.

What you’ll be doing:

• Designing and executing CHO cell culture experiments using small-scale and high-throughput models
• Running CRISPR knockout screens and transfections for gene editing
• Applying molecular and cell biology assays (qRT-PCR, Western blotting, ELISA)
• Operating the BD FACSAria Fusion Flow Cytometer for single cell cloning and analysis
• Supporting cell line development using technologies like Beacon and Ambr15
• Writing SOPs, maintaining lab documentation, and training junior scientists
• Ensuring lab safety standards and participating in out-of-hours cell culture as needed

What we’re looking for:

• BSc/MSc with 3+ years or PhD with 1+ years in a biotech or pharma environment
• Strong experience with CHO suspension cells, single-cell workflows, and genotyping
• Skilled in CRISPR/Cas9 techniques and FACS-based cell sorting
• Comfortable working independently and collaboratively in a fast-paced lab
• Experienced in experimental planning, troubleshooting, and scientific communication

Nice to have:

• Familiarity with Beacon, Ambr15, or 96-well high-throughput models
• Experience working safely with lentiviral plasmid systems in a CAT2 environment
• Understanding of monoclonal antibody production and critical quality attributes (CQA)

Looking to play a key role in breakthrough biologics research? Apply now!