Associate Scientist - Antibody Discovery

TN United Kingdom; Great Abington; On-site; GBP 30,000 - 50,000; Full time

Job summary

An established industry player in cancer research is seeking an Associate Scientist to join their antibody discovery team. This role offers an exciting opportunity for recent graduates or lab technicians eager to expand their skills in a supportive environment. You will work closely with a multidisciplinary team to generate therapeutic antibodies, gaining hands-on experience with advanced protein engineering techniques and purification methods. With a strong focus on innovation and inclusivity, this position allows you to contribute meaningfully to the fight against cancer while developing your career in a dynamic and collaborative setting.

Benefits

Career Development Opportunities

Supportive Working Environment

Work-Life Balance Tools

Benefits Package

Qualifications

• Degree in a relevant field required for the role.
• Knowledge of protein expression and purification methods is necessary.

Responsibilities

• Generate antibody and antibody fragment reagents using bacterial and mammalian systems.
• Perform purification of antibodies and proteins using AKTA and other platforms.

Skills

Protein Engineering

High Throughput Screening

Molecular Biology Techniques

Biochemical Assays

Cell-Based Assays

Education

Degree in a Relevant Field

Tools

AKTA Instrumentation

SDS-PAGE

HPLC

Western Blotting

Job description

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Associate Scientist - Antibody Discovery, Great Abington

Client:

Cancer Research UK

Location:

Great Abington, United Kingdom

Job Category:

Other

EU work permit required:

Yes

Job Reference:

c2f40a29ab42

Job Views:

5

Posted:

05.05.2025

Expiry Date:

19.06.2025

Job Description:

At Cancer Research UK, we exist to beat cancer

Cancer Research UK's antibody discovery team has a position available for an associate scientist to join us in our vision to bring forward the day when all cancers are conquered.

About CRUK Drug Discovery

As the world’s biggest medical research charity, we’ve helped bring eleven new cancer drugs to market. However, there is still an urgent need to bring more effective treatments to patients faster.

We have recently developed a new approach to driving therapeutic innovation through the creation of Cancer Research Horizons (CRH). We have brought together Cancer Research UK’s established drug discovery teams under one organization and leadership, combining our pipeline of biology, technology platforms, and clinical expertise to:

• Bring new treatments to patients faster
• Tackle challenges in discovering cancer drugs by seeking radical ideas and embracing risk

This is a great opportunity for an ambitious, proactive scientist eager to start their career. You will gain exposure to techniques in protein engineering, high throughput screening, and protein science in a supportive environment with experienced colleagues. You will contribute to pipeline and technology development projects, work in an inclusive environment that encourages creativity, and participate in conferences, poster presentations, and publications. You’ll be surrounded by people dedicated to beating cancer.

What will I be doing?

This lab-based role involves working with a multidisciplinary drug discovery team to deliver therapeutic antibodies against oncology targets. You will support the delivery of key protein reagents for antibody discovery campaigns.

As an Associate Scientist, you will:

• Generate antibody and antibody fragment reagents using bacterial and mammalian expression systems
• Perform purification of antibodies and proteins using AKTA and other platforms
• QC antibodies with SDS-PAGE, HPLC, and Western blotting
• Maintain inventory and support supply of reagents
• Perform molecular biology tasks like restriction digestion and cloning
• Operate laboratory equipment

What are you looking for?

The role is suitable for recent graduates or current lab technicians seeking to expand their skills. Candidates should demonstrate:

• A degree in a relevant field
• Knowledge of protein expression and purification methods
• Experience with biochemical or cell-based assays
• Knowledge of molecular biology techniques for constructing expression vectors
• Experience with protein purification and AKTA instrumentation (desired)
• Experience with mammalian transient expression (desired)
• Interest in learning phage display technology

Our organization values ambition, professionalism, positive impact, and inclusivity. We seek candidates who embody these values and are motivated to beat cancer.

What will I gain?

We offer a supportive working environment, benefits, career development opportunities, and tools to help you balance work and personal life. Visit our careers webpage to explore benefits.

How do I apply?

We use an anonymized shortlisting process to promote equality, diversity, and inclusion. CVs are required for all applications, but we won’t view them until invited for an interview. Please complete the work history section of the online application form for fair assessment.