Associate Scientist - Antibody Discovery

Cancer Research UK; Great Abington; On-site; GBP 27,000 - 33,000; Full time

Job summary

Cancer Research UK seeks an Associate Scientist for its antibody discovery team in Great Abington. Ideal candidates will have a relevant degree and lab experience, eager to support therapeutic antibody campaigns and work in a collaborative environment focused on innovative drug discovery.

Benefits

Supportive work environment

Career development opportunities

Qualifications

• Recent graduates with lab experience or current lab technicians welcome.
• Demonstrate knowledge of protein purification and lab techniques.
• Experience with mammalian transient expression is desirable.

Responsibilities

• Generate antibody and antibody fragment reagents.
• Perform purification of antibodies using AKTA.
• Maintain inventory and support supply of reagents.

Skills

Knowledge of protein expression and purification methods

Knowledge of biochemical and cell-based assays

Experience with molecular biology techniques

Interest in learning phage display technology

Education

Relevant degree

Tools

AKTA

Job description

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Associate Scientist - Antibody Discovery, Great Abington

Client:

Cancer Research UK

Location:

Great Abington, United Kingdom

Job Category:

Other

EU work permit required: Yes

Job Reference:

c2f40a29ab42

Job Views:

6

Posted:

02.06.2025

Expiry Date:

17.07.2025

Job Description:

At Cancer Research UK, we exist to beat cancer

Cancer Research UK’s antibody discovery team has a position available for an Associate Scientist to join us in our vision to bring forward the day when all cancers are conquered.

About CRUK Drug Discovery

As the world’s biggest medical research charity, we’ve helped bring eleven new cancer drugs to market. However, there is still an urgent need to bring more effective treatments to patients faster.

We have recently developed a new approach to therapeutic innovation through Cancer Research Horizons (CRH). We have brought together Cancer Research UK’s established drug discovery teams under one organization and leadership, combining our pipeline of biology, cutting-edge technology platforms, and clinical expertise to:

• Bring new treatments to patients faster
• Tackle challenges in discovering cancer drugs by seeking radical ideas and embracing risk

This is a great opportunity for an ambitious, proactive scientist eager to start their career. You will gain exposure to techniques across protein engineering, high throughput screening, and protein science in a flexible environment with support from experienced colleagues. You will contribute to pipeline and technology projects, work in an inclusive environment, and participate in conferences, poster presentations, talks, and publications.

What will I be doing?

This lab-based role involves working with a multidisciplinary drug discovery team to deliver therapeutic antibodies against oncology targets. You will support the delivery of protein reagents for antibody discovery campaigns.

As an Associate Scientist, you will:

• Generate antibody and antibody fragment reagents using bacterial and mammalian expression systems
• Perform purification of antibodies and proteins using AKTA and other platforms
• QC antibodies with SDS-PAGE, HPLC, and Western blotting
• Maintain inventory and support supply of reagents
• Perform molecular biology tasks such as restriction digest and cloning
• Operate laboratory equipment

What are you looking for?

The role suits recent graduates with lab experience or current lab technicians seeking to expand their skills. Candidates should demonstrate:

• A relevant degree
• Knowledge of protein expression and purification methods
• Knowledge of biochemical and cell-based assays
• Experience with molecular biology techniques for constructing expression vectors
• Experience with protein purification and AKTA is desirable
• Experience with mammalian transient expression is desirable
• Interest in learning phage display technology

Our values are:

• Bold: Act with ambition, courage, and determination
• Credible: Act with rigour and professionalism
• Human: Have a positive impact on people
• Together: Act inclusively and collaboratively

We encourage candidates to embody these values to drive progress against our mission to beat cancer.

If you're interested but unsure if you have the right skills, we still welcome your application.

What will I gain?

We offer a supportive environment, benefits, career development opportunities, and tools to help balance work and personal life. Explore our benefits on our careers webpage.

How do I apply?

We use anonymized shortlisting to promote equality, diversity, and inclusion. CVs are required but reviewed only after invitation to interview. Please complete the work history section of the online application form for fair assessment.