Associate Scientist Analytical Development - Oxford

ZipRecruiter; Oxford; On-site; GBP 30,000 - 45,000; Full time

Job summary

A pioneering biotechnology company in Oxford seeks an Associate Scientist in Analytical Development. You will focus on developing and qualifying analytical methods using chromatography to support biopharmaceutical production. Ideal candidates possess a background in recombinant proteins and expertise in HPLC. The role promotes a collaborative environment valuing diversity and continuous learning.

Qualifications

• Background in recombinant protein or antibody/biopharmaceutical analytical development with 1+ years' experience.
• Hands-on expertise with HPLC/UHPLC for protein analysis.
• Experience working in a diverse team environment.

Responsibilities

• Developing and qualifying chromatographic methods.
• Contributing to writing operating procedures and study reports.
• Ensuring laboratory records are accurate and up to date.

Skills

HPLC/UHPLC expertise

Electrophoretic methods

Attention to detail

Team collaboration

Education

BSc or MSc in biochemistry, biotechnology, or related discipline

Tools

HPLC

Electrophoresis equipment

Job description

Job Description

Associate Scientist Analytical Development - Oxford

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new class of transformative medicines which address unmet patient needs in oncology, infectious diseases, and autoimmune diseases. Our leaders in R&D are internationally recognized as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new class of precision-engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases, and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset.

We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE embodies our shared values and drives our mission.

We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another. Immunocore is proud to be an equal opportunity employer. We are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered.

We encourage applications from individuals of all backgrounds, regardless of race, color, sex, gender identity, sexual orientation, disability status, or any other characteristic protected by law.

As Associate Scientist in Analytical Development, you will contribute to developing analytical methods to support Immunocore's expanding pipeline of biopharmaceuticals. The core focus will be development and transfer of chromatography and electrophoresis-based methods for lot release and stability testing of protein products. Working closely with experienced scientists and cross-functional teams, you'll contribute to study reports and operating procedures, drive continuous improvement, and expand your technical expertise in a dynamic, collaborative environment.

KEY RESPONSIBILITIES

1. Running pre-established experimental investigations, with guidance from line managers, a mentor or colleagues.
2. Developing and qualifying (ultra) high-performance liquid chromatography (UHPLC), gel / capillary electrophoresis that support stability, lot release, and characterization testing as part of biopharmaceutical product development.
3. Supporting process development by testing process intermediates and performing investigations.
4. Contributing to the writing of operating procedures and study reports.
5. Prioritizing work according to experimental priorities and deadlines; raising issues or concerns with managers or colleagues for resolution.
6. Actively developing technical knowledge, drawing on the experience of others and self-learning.
7. Ensuring laboratory records and data are up to date, accurate, and recorded to the correct standard, consulting with mentors or colleagues when unsure.
8. Attending training on the use of technical instruments, using equipment appropriately, correctly, and tidily.
9. Complying with all Health & Safety requirements, attending appropriate training programs.

PERSON SPECIFICATION

Experience & Knowledge (Essential)

• A background in recombinant protein or antibody/biopharmaceutical analytical development or QC, with one or more years' industry experience.
• Hands-on expertise with HPLC/UHPLC (e.g., size exclusion, ion exchange, reverse phase, hydrophobic interaction) for protein analysis.
• Hands-on expertise with electrophoretic methods (e.g., CE-SDS) for protein analysis.
• Ability to record results and information concisely, accurately, and promptly.
• Willingness to learn new practices through observation, self-learning, and curiosity.
• Experience working actively in a diverse team environment.

Desirable

• Experience with imaging capillary IEF (icIEF), Western blotting.
• Knowledge of GMP.
• Experience with lab organization and maintenance.
• Proactive attitude towards ensuring high-quality work and seeking additional responsibilities.
• Familiarity with assay qualification/validation principles, such as robustness and suitability.

Education & Qualifications

BSc or MSc in biochemistry, biotechnology, or a related discipline.