Associate Process Development Scientist, Downstream - Oxford

ZipRecruiter; Oxford; On-site; GBP 30,000 - 45,000; Full time

Job summary

A pioneering biotechnology company in Oxford is seeking an Associate Process Development Scientist to drive downstream process development of drug candidates. The role involves conducting experiments in protein purification and collaborating in a dynamic lab environment, requiring technical expertise and a commitment to safety and innovation.

Qualifications

• Experience in biopharmaceutical laboratories and protein purification.
• Essential GCSEs; desirable BSc/MSc in relevant fields.
• Strong team player with robust record-keeping skills.

Responsibilities

• Conduct experiments and interpret results.
• Follow protocols and maintain accurate lab records.
• Communicate findings effectively in meetings.

Skills

Protein purification

Microbial culture

Aseptic techniques

Molecular biology

Biochemistry

Education

GCSEs in mathematics, English, and science

BSc. or MSc. in protein engineering, microbiology, biochemistry, molecular biology

Tools

AKTA purification systems

Laboratory analysis software

Job description

Job Description

Associate Process Development Scientist, Downstream - Oxford

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company dedicated to developing and commercializing transformative medicines that address unmet patient needs in oncology, infectious diseases, and autoimmune diseases. Our R&D leaders are recognized globally as some of the industry's most successful drug developers. We foster an environment where innovation and collaboration thrive, aiming to answer the big questions in medicine.

We focus on delivering first-in-class biological therapies using our innovative soluble TCR platform. Our ImmTAX molecules represent a new class of precision-engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical needs. At Immunocore, we value our employees as our greatest asset and are committed to an inclusive workplace where everyone feels valued, respected, and empowered.

We encourage applications from individuals of all backgrounds, regardless of race, gender, ethnicity, sexual orientation, gender identity, age, disability, or any other characteristic protected by law.

Role Overview:

This role involves conducting experimental investigations to drive downstream process development of emerging drug candidates, supporting reagents, and establishing production processes for manufacturing and clinical development. Protein purification is central to this role, requiring an understanding of protein characteristics, chromatography, separation techniques, and analytical assessments such as SDS-PAGE and HPLC. The ideal candidate is a strong team player, eager to learn and develop in downstream process development, with robust record-keeping and reporting skills.

Key Responsibilities:

• Conduct experiments, interpret results, and respond accordingly.
• Follow experimental protocols and prepare reports.
• Maintain and enhance technical knowledge through self-study, conferences, and training.
• Keep accurate records in laboratory notebooks and follow company procedures.
• Operate laboratory equipment safely, report faults promptly, and adhere to health and safety policies.
• Communicate research findings effectively in meetings and reports.

Experience and Knowledge:

• Experience in microbial or mammalian expression, biochemistry, molecular biology, analytical, or biopharmaceutical laboratories.
• Skills in protein purification, microbial culture, aseptic techniques, and basic protein biochemistry or molecular biology.
• Familiarity with laboratory equipment and record-keeping standards.

Desirable Skills:

• AKTA purification systems and method design.
• Molecular biology techniques.
• Biophysical characterization of proteins.
• Mammalian expression systems.
• Knowledge of cGMP and biopharmaceutical manufacturing.
• Design of Experiments (DoE).
• Proficiency in laboratory analysis software.

Education and Qualifications:

• Essential: GCSEs in mathematics, English, and science.
• Desirable: BSc. or MSc. in protein engineering, microbiology, biochemistry, molecular biology, or related fields.