Associate Director, Immunotoxicology

AstraZeneca GmbH; Cambridge; On-site; GBP 80,000 - 100,000; Full time

Job summary

A leading company in the pharmaceutical industry is seeking an Associate Director in Immunotoxicology to develop innovative solutions for immune safety. This role involves designing strategies, mentoring team members, and collaborating across disciplines to enhance drug safety. Candidates should have a strong background in immunology and toxicology, with excellent communication skills and the ability to work independently. Join a dynamic team to make a significant impact on patient outcomes.

Qualifications

• PhD in immunology with postdoc experience or equivalent industrial experience.
• Extensive practical experience with in vitro and ex vivo cell-based assays.

Responsibilities

• Designing innovative immunotoxicology strategies to mitigate adverse reactions.
• Leading multiple projects and mentoring team members.

Skills

Communication

Teamwork

Problem Solving

Education

Bachelor's degree in immunology, cell biology, molecular biology, or pharmacology

PhD in an immunology field

Tools

Flow Cytometry

Multiplexing Technologies

Job description

Job Title: Associate Director, Immunotoxicology

Locations: Cambridge, UK

Salary: Competitive+ Excellent Employee Benefits!

Applications Deadline: June 1st

Introduction to role:
Are you ready to make a significant impact in the field of Immunotoxicology? Join our Immune Safety department within Safety Sciences, where we work with diverse drug modalities targeting various disease indications, particularly those involving the immune system. We are excited to offer an opportunity to join our Immunotoxicology Group as an Associate Director. In this pivotal role, you will deliver safe and innovative medicines across our Immunology disease portfolio. Your expertise will be crucial in developing bespoke solutions to address immune safety questions, focusing on mechanistic understanding and mitigation of unwanted immune-mediated adverse reactions.

This role is based at our vibrant R&D site in Cambridge (UK), where you will collaborate with experts across multiple disciplines to enhance your skills and knowledge.

Accountabilities:
As an Associate Director of Immunotoxicology at AstraZeneca, your main responsibilities will include:

• Designing, delivering, and interpreting innovative immunotoxicology strategies to predict and mitigate unwanted immune-mediated adverse reactions.

• Supporting immunotoxicological evaluation and strategies for project progression involving oligonucleotides, synthetic molecules, and peptides.

• Integrating multiple strands of knowledge into coherent immunotoxicology strategies and investigations.

• Leading and prioritizing multiple projects and tasks in line with team objectives.

• Presenting expert advice on immunotoxicology strategy and mitigations to safety representatives and project teams.

• Mentoring and guiding team members in immunology hypotheses and practical strategies.

• Continuously developing your expertise and scientific network through publications and conference presentations.

Essential Skills/Experience:

• Bachelor's degree or equivalent qualification in immunology, cell biology, molecular biology, or pharmacology.

• PhD in an immunology field with multiple postdoc positions or equivalent industrial experience in immunology and toxicology.

• Knowledge and practical experience in immunology/immunotoxicology with an understanding of potential adverse outcomes of immune modulation.

• Extensive practical experience with in vitro and ex vivo cell-based assay systems.

• Comprehensive capabilities in immune biomarker assessment, multiplexing technologies, and imaging technologies. Exceptional flow cytometry skills are essential.

• Understanding of the drug-development process and toxicology landscape for different drug modalities.

• Excellent verbal and written communication, interpersonal, and influencing skills.

• Ability to work independently and within a team environment.

• Willingness to challenge conventional thinking while understanding regulatory frameworks.

• Ability to follow Good Laboratory Science standards, Safety, Health, and Environment standards, the Human Tissue Act, and other relevant regulations.

Desirable Skills/Experience:

• Understanding of immunology across preclinical toxicology in vivo models.

• Knowledge and practical experience of flow cytometry and multiplex analysis.

• Experience working within a toxicology laboratory environment.

• Understanding of immunotoxicology and/or toxicology biomarker application in vivo.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we are driven by a shared belief in the power of science to redefine what's possible. Our commitment to research and development fuels our mission to make a meaningful impact on patients' lives. By integrating digital, data science, and AI, we fast-forward our research to ensure that work born in a lab can make a real difference globally. Our inclusive environment fosters collaboration across academia, biotechs, and industry, creating swift impacts on disease. Join us to explore new ways of handling complex diseases and be part of a team that continuously learns and innovates.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Ready to make a difference? Apply now to join our team as an Associate Director in Immunotoxicology!