Aseptic Services Manager and Deputy Associate Chief

NHS; London; On-site; GBP 82,000 - 94,000; Full time

Job summary

Join a pioneering organization at the forefront of cancer care! This role as an Aseptic Services Manager offers a unique opportunity to lead the design and implementation of a state-of-the-art facility dedicated to paediatric cancer treatments. You will play a crucial role in shaping the future of advanced therapy care, ensuring compliance with regulatory standards, and collaborating with top professionals across various departments. Your expertise will directly impact patient outcomes, making this position not only a career advancement but also a chance to make a significant difference in the lives of those in need. Be part of an innovative team that values quality and patient care!

Qualifications

• Senior management experience in aseptic facilities.
• Experience in managing clinical trial operations and audits.

Responsibilities

• Lead the technical project team and ensure compliance with quality standards.
• Coordinate with clinical teams for service readiness and capacity planning.

Skills

Leadership skills

Risk management

Guidance provision for manufacturing teams

Capacity evaluation

Education

Higher degree in pharmaceutical technology

Active registration with the General Pharmaceutical Council

Job description

Aseptic Services Manager and Deputy Associate Chief

Guy's and St Thomas' NHS Foundation Trust

An exceptional opportunity has arisen to provide leadership and quality sign-off for the design, build, and validation of a purpose-built Paediatric Cancer and ATMP facility at St Thomas' Hospital, opening in September 2026. The role involves leading the core functions of the new unit and the existing Guy's Cancer Centre chemotherapy and advanced therapy facility, with overall responsibility for the services provided.

Main duties of the job

• Provide technical leadership for all aspects of chemotherapy (including clinical trials) and advanced therapies services at St Thomas' and Guy's Cancer Centre, and Guy's Pharmacy Containment Suite.
• Lead, develop, and evaluate a comprehensive aseptic service covering adult and paediatric chemotherapy, advanced therapies, and aseptic manufacturing, aligning with objectives set with relevant stakeholders.
• Strategically develop aseptic services within and outside the Trust, in line with NHS regional and national priorities.
• Manage research and development within aseptic services, ensuring projects are delivered on time in collaboration with clinical trials teams.

About us

Join us at the forefront of innovation in cancer and advanced therapy care! Guy's & St Thomas' NHS Foundation Trust is building a state-of-the-art Pharmacy Aseptic Unit at St Thomas' to prepare chemotherapy and advanced therapies. This project aims to transform patient care.

Why join us?

• Be part of innovation: Contribute to designing and launching a modern aseptic facility.
• Make an impact: Your expertise will improve outcomes for patients requiring specialized treatments.
• Collaborate with top professionals across various departments.
• Shape the future: Influence every stage from specification to operational delivery, prioritizing quality and patient care.

What you'll be doing:

• Leading technical aspects of the new unit's design and operations.
• Ensuring compliance with regulatory and quality standards.
• Participating in cross-functional project teams to create a future-ready facility.
• Ensuring the facility meets evolving medical needs.

Job responsibilities

Phase 1 Project Implementation

• Lead and support the technical project team, deputize as needed.
• Prepare and approve procedures and validation documents.
• Coordinate with the Transformation Manager to meet project timelines.
• Select contractors, support procurement, and review tenders.
• Report on project progress to stakeholders.
• Oversee validation activities and review documentation.
• Develop start-up plans and ensure integration with existing services.
• Represent the facility in inspections and provide project updates.
• Coordinate with clinical teams to ensure service readiness and capacity planning.
• Manage new product introduction and process validation.
• Develop strategies for a robust manufacturing workforce.

Post-project responsibilities are detailed within the full job description.

Person Specification

Qualifications

• Active registration with the General Pharmaceutical Council without restrictions.
• Higher degree (e.g., MSc) in pharmaceutical technology, quality assurance, or equivalent experience.

Experience

• Senior management experience in aseptic facilities.
• Experience managing clinical trial operations and audits per GMP/GCP.
• Experience in designing, building, and commissioning aseptic facilities.
• Experience expanding technical services to meet patient needs and reduce risks.

Knowledge

• Contamination control strategies within aseptic services.
• Knowledge of EudraLex, MHRA, QAAPs, and pharmacopoeial requirements.
• Legislation related to medicines (e.g., HMR 2012/1916).
• Advanced understanding of isolators and laminar airflow technology.
• Validation requirements for pharmaceutical facilities and equipment.
• Best practices in the governance and preparation of AT(I)MPs.

Skills

• Leadership and motivation skills to inspire high performance.
• Guidance provision for manufacturing teams to resolve issues.
• Capacity to evaluate workload and service development impacts.
• Risk management skills.

Disclosure and Barring Service Check

This role requires a DBS check due to the nature of the work involving regulated activities.

Salary: £82,462 to £93,773 per annum, inclusive of HCA.