Applications Bioinformatician

Oxford Nanopore Technologies; Oxford; On-site; GBP 40,000 - 60,000; Full time

Job summary

Une entreprise innovante dans le secteur de la biotechnologie recherche un Applications Bioinformatician pour optimiser les protocoles de séquençage et développer des pipelines d'analyse. Le rôle implique la collaboration avec des scientifiques en laboratoire et l'apport de solutions de séquençage à travers différents secteurs. Le candidat idéal possède un doctorat en Bioinformatique, ainsi qu'une expérience approfondie en analyse de séquences et en développement de logiciels.

Qualifications

• PhD en Bioinformatique ou domaine connexe requis.
• Compétences en développement de pipelines et analyse de données NGS.
• Capacité à adapter les outils bioinformatiques pour des résultats ciblés.

Responsibilities

• Développer des workflows et réaliser des analyses de données.
• Collaborer étroitement avec les scientifiques en laboratoire.
• Contribuer à la conception de nouveaux tests moléculaires.

Skills

DNA/RNA sequence analysis

Pipeline development

Scripting (Python, R)

Education

PhD in Genetics, Bioinformatics, or related field

Tools

Nextflow

Job description

Job Description

Who we are

Oxford Nanopore Technologies (ONT) has developed portable and scalable DNA and RNA sequencing platforms with the goal of enabling the sequencing of any living thing, by anyone, anywhere. The real-time data generation, scalability, and portability of our devices make decentralised and on-location sequencing a practical solution-empowering industries to harness the power of genomic information in diverse settings.
The role: Applications Bioinformatician

Reporting to the Applications Manager, Genomics Applications, this is a computational role working alongside lab scientists to:

• Optimise application-specific sequencing protocols
• Develop end-to-end sequencing workflows
• Build associated data analysis pipelines

You'll support our Business Development and Strategic Marketing teams by delivering sequencing solutions across sectors such as biopharma, veterinary science, agriculture, food safety, and bioproduction.

We're looking for a skilled bioinformatician with experience in DNA/RNA sequence analysis and pipeline development to join the Genomics Applications team in Oxford.
Key responsibilities

• Contribute to the design of new application-specific molecular assays
• Develop prototype workflows and perform data analysis
• Design, optimise, and maintain data analysis pipelines
• Collaborate closely with wet lab scientists to deliver complete sequencing solutions
• Follow best practices in software development and maintain thorough documentation
• Present and report findings to internal and external stakeholders
• Work cross-functionally with teams in Development, Product Management, and Marketing

Qualifications, experience & skills

• PhD (or equivalent industry experience) in Genetics, Genomics, Bioinformatics, Biological Sciences, or Computer Science with a strong bioinformatics component
• Experience with assay design (desirable)
• Proficiency in NGS data analysis and variant calling
• Familiarity with methylation-calling and real-time analysis (ideal but not essential)
• Ability to adapt or modify bioinformatics tools/pipelines for targeted outcomes
• Strong scripting skills (e.g., Python, R) and experience with workflow tools like Nextflow
• Good understanding of software development practices (e.g., version control)
• Proven ability to develop robust software and pipelines
• Excellent communication and interpersonal skills
• High attention to detail, strong organisational skills, and a solid work ethic
• Exceptional time and project management capabilities

Oxford Nanopore Technologies is committed to fair and unbiased hiring practices. We welcome applicants from all backgrounds and assess all candidates solely on their merits, qualifications, and ability to perform the role.

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About Us

Oxford Nanopore's goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology enabling the real-time, high-performance, accessible and scalable analysis of DNA and RNA. The technology is used in more than 100 countries to understand the biology of humans and diseases, plants, animals, bacteria, viruses and whole environments.

Oxford Nanopore was founded in 2005 as a spin-out from the University of Oxford and now employs over 1000 employees around the world.