Advanced Research Assistant

Genome Research Limited (GRL); Hinxton; Hybrid; GBP 32,000 - 39,000; Full time

Job summary

Genome Research Limited is seeking an Advanced Research Assistant for a fixed-term role within the Human Genetics Programme. The role involves working on a significant project utilizing single cell genomics to explore factors driving inflammatory bowel disease and biomarkers for long-term patient outcomes. This position aims to enhance human health through multidisciplinary collaboration, underlined by a commitment to excellence in scientific research.

Benefits

Comprehensive wellbeing strategies

Technician development support

Hybrid working arrangements

Qualifications

• Experience handling human tissue, blood, and mammalian cells.
• Experience with molecular biology techniques like PCR and RT-PCR.
• Strong organizational and communication skills required.

Responsibilities

• Liaise with clinical teams to acquire human tissue and blood samples.
• Assist with processing samples for single-cell omics assays.
• Support computational analysts regarding experimental processes.

Skills

Attention to detail

Organizational skills

Communication skills

Team collaboration

Education

Masters in Biological Sciences or equivalent

Tools

PCR

RT-PCR

Job description

Advanced Research Assistant page is loaded

Advanced Research Assistant

Apply locations Hinxton, Cambridgeshire | Time type: Full time | Posted on: Posted Yesterday | Job requisition id: JR102920

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenges.

We are recruiting an Advanced Research Assistant for a 2-year fixed-term contract to join our Human Genetics Programme.

About the Role:

This is an exciting opportunity to join a multidisciplinary project applying single cell genomics to cells isolated from patients with inflammatory bowel disease (IBD) or healthy individuals. The goal of the project Open-IBD is to provide a deep multi-omic characterization of early-stage IBD in a large cohort of 1000 newly diagnosed patients to nominate causal factors driving IBD pathology and identify biomarkers of long-term outcomes in IBD, including disease progression and drug response. This project is overseen by Open Targets, a public-private partnership involving the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and leading pharmaceutical companies GSK, Sanofi, MSD, Pfizer, and Genentech.

About Us:

The Open Targets research programme generates and analyzes data to connect targets to diseases, assess the strength of this evidence, and help identify and prioritize targets for drug discovery.

About You:

You will be based at the WSI, working closely with Dr. Cristina Cotobal Martin and other collaborators. This laboratory-based role involves liaising with clinical teams across the UK to acquire human tissue/blood samples and assist with processing these for single cell omics assays. Experience in handling human tissue, PBMCs, and plasma from blood samples is required. Training on SOPs will be provided.

Experience with large-scale data, accurate record keeping, high throughput assays, robotics, and automation is advantageous. You will support computational analysts regarding experimental processes.

Essential Skills:

• Masters or equivalent in Biological Sciences or related experience
• Experience handling human tissue, blood, and mammalian cells
• Experience with molecular biology techniques such as PCR, RT-PCR
• Attention to detail and adherence to SOPs
• Strong organizational, communication skills, and good work ethic
• Team player with collaborative skills

Competencies and Behaviours:

• Strong organizational and communication skills
• Collaborative team player

Other Information:

Salary: £32,691–£38,838 per annum (dependent on skills and experience)

Application Process:

Please submit your CV and cover letter addressing the criteria above.

Closing Date: 25th June 2025

Hybrid Working at Wellcome Sanger:

We support hybrid working arrangements to promote work-life balance and facilitate collaboration, tailored to role requirements.

Equality, Diversity, and Inclusion:

We are committed to creating an inclusive environment and value diversity in our workforce, supporting various staff networks and promoting equality.

Our Benefits:

We offer comprehensive wellbeing strategies and are committed to supporting technician development and recognition.

About Us

Life at the Sanger Institute involves tackling challenging genomic research, shaping the future with innovative science, and fostering a diverse and inclusive culture.