Accelerated Knowledge Transfer (AKT) Associate in Automated Organic Synthesis

University of Bath; Bath; Vor Ort; GBP 30.000 - 36.000; Vollzeit

Zusammenfassung

The University of Bath invites applications for an AKT Associate to join a collaborative project with Almac Discovery Limited to automate synthesis workflows and generate small-molecule libraries.

Working under the supervision of Dr Alex Cresswell and Dr Colin O'Dowd, you will transfer innovative automated synthesis methodologies into an industrial drug discovery setting while broadening your knowledge and expertise.

Qualifikationen

• Strong practical expertise in synthetic organic chemistry.
• Experience of reaction optimisation and analytical characterisation.
• The ability to design, execute and interpret complex experimental programmes independently.
• Excellent organisational skills and attention to detail.
• Strong written and verbal communication skills.
• The ability to work effectively across academic and industrial environments.

Aufgaben

• Demonstrate and optimise automated synthetic chemistry workflows.
• Design and produce representative small-molecule screening libraries.
• Evaluate workflow robustness, reproducibility and operational efficiency.
• Work closely with medicinal chemistry, biology and analytical teams.
• Develop standard operating procedures and supporting documentation.
• Support the transfer of knowledge and capability into Almac Discovery's research teams.
• Contribute to future plans for technology expansion and commercial exploitation.

Kenntnisse

Synthetic Organic Chemistry

Reaction Optimisation

Analytical Characterisation

Independent Experimental Design

Excellent Organisation

Strong Communication

Industry-Academia Collaboration

Jobbeschreibung

An exciting opportunity has arisen for a highly motivated chemist to join a collaborative Accelerated Knowledge Transfer (AKT) project between the University of Bath and Almac Discovery Limited, a leading early-stage drug discovery company within the Almac Group.

About the role

The project will establish an automated workflow for rapid production of novel small-molecule libraries, enabling Almac Discovery to accelerate early-stage drug discovery, reduce reliance on outsourced compound synthesis, and strengthen its capability to identify promising new medicines more quickly and cost-effectively.

Whilst working on this unique project as an AKT Associate, applying your academic skills to an industrially focused project, you will broaden your knowledge and expertise, and be supported by an Industrial and an academic supervisor.

Working under the supervision of Dr Alex Cresswell, Reader in Organic Chemistry and Co-Lead of the Bath Centre for Drug Discovery, and Dr Colin O'Dowd, Vice President of Medicinal Chemistry at Almac Discovery, you will play a key role in transferring innovative automated synthesis methodologies into an industrial drug discovery environment.

As the AKT Associate, you will:

• Demonstrate and optimise automated synthetic chemistry workflows.
• Design and produce representative small-molecule screening libraries.
• Evaluate workflow robustness, reproducibility and operational efficiency.
• Work closely with medicinal chemistry, biology and analytical teams.
• Develop standard operating procedures and supporting documentation.
• Support the transfer of knowledge and capability into Almac Discovery's research teams.
• Contribute to future plans for technology expansion and commercial exploitation.

The post will offer the following benefits:

• Work at the interface of academic innovation and industrial drug discovery.
• Gain experience of technology transfer within a commercially focused research environment.
• Collaborate with world-leading experts in synthetic chemistry and drug discovery.
• Build valuable industrial and translational research experience within the life sciences sector.

We welcome applications from candidates who have:

• Strong practical expertise in synthetic organic chemistry.
• Experience of reaction optimisation and analytical characterisation.
• The ability to design, execute and interpret complex experimental programmes independently.
• Excellent organisational skills and attention to detail.
• Strong written and verbal communication skills.
• The ability to work effectively across academic and industrial environments.

This AKT project is funded by UKRI through Innovate UK . This programme has been adesigned to create short-term collaborations between a university and business to deliver a rapid and targeted intervention to accelerate the development of an innovation project, with potential for significant impact on the business. AKT projects are delivered by graduates who benefit from the opportunity to work on a strategically relevant project within industry, whilst receiving support and guidance from university academics. More information about the Accelerated Knowledge Transfer programme can be found at: https://www.ktp-uk.org/accelerated-knowledge-transfer/

Further information

Interviews will be held on Friday 23 October.

This is a fixed-term role for a period of 3 months, and the role must start no later than 13 November 2026.

We consider ourselves to be a university where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equity and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students and encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on the university. We are committed to maintaining a safe and secure environment for our students, staff, and community by reinforcing our Safer Recruitment commitment.

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• Staff support groups and networks
• A network of Staff Wellbeing Champions
• A suite of tools, resources and frameworks that enable you to be at your best and thrive

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Right to Work in the UK: We do not assess immigration or right to work status until offer stage. Being invited to interview does not guarantee you are eligible for visa sponsorship and all offers are conditional on meeting right to work requirements. Further information is available on our application support webpage.

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