AAV Scientist

taylorollinson Ltd; United Kingdom; On-site; GBP 30,000 - 40,000; Full time

Job summary

A leading biotechnology company near Cambridge is hiring a Scientist to support their AAV and cell biology projects. The role involves developing AAV vectors, lab analysis, and process improvement initiatives. Ideal candidates will hold a BSc/MSc and have AAV production experience within mammalian cell lines.

Benefits

Competitive salary

Progression options

Private pension

Qualifications

• Extensive AAV production experience using HEK 293 cells is essential.
• Strong experience in laboratory analysis techniques such as ELISA, SDS-PAGE, qPCR.
• Prior experience in bacterial cloning is desired.

Responsibilities

• Development and optimisation of AAV vectors for gene therapy.
• Production and purification of AAVs using mammalian cell culture.
• Laboratory analysis of AAVs using various techniques.

Skills

AAV production

Mammalian cell culture

Laboratory analysis

Education

BSc / MSc / PhD in biological / biotechnology discipline

Job description

Salary: £30,000 - £40,000 depending on experience, this may differ.

Our client is an innovative biotechnology company based outside of the centre of Cambridge. They have built an enzymatic platform to synthesise DNA, providing exciting possibilities for ensuring cheaper, faster and more accurate DNA / RNA / gene constructs than traditional plasmid-based methods. They also supportdrug discovery projects within the gene therapy sector using adeno-associated viruses (AAV). In a key phase of their growth, our client is looking to bring a Scientist into the team to support the AAV and cell biology section of the business. This role will require the successful candidate to have previous AAV expression experience within mammalian cell lines (HEK-293 etc)

The Opportunity

This is an opportunity for a scientist who holds a BSc/MSc in a Biology focused role with at least one year of experience within AAV expression and production. This can be gained during your degree, or in industry. This role will involve the following:

• Development and optimisation of AAV vectors for use within gene therapy products.
• Production and purification of AAVs using mammalian cell culture systems (HEK 293).
• Being part of process improvement initiatives for AAV production.
• Laboratory analysis of the AAVs using SDS-PAGE, qPCR, flow cytometry, ELISA, gel electrophoresis etc.
• Recording of data and ensuring the data is up to date and reliable.
• Participate in team meetings and trainings as and when required.
• Support in other areas of the business as and when required.
• Following of laboratory and company SOPs.

Skills and Experience Needed

The ideal candidate will have the following:

• BSc / MSc / PhD in a biological / biotechnology discipline (essential)
• Extensive AAV production experience using HEK 293 cells (essential)
• Must be competent in various aspects of AAV production e.g. transfection, mammalian cell culture, AAV purification (essential)
• Strong experience in some laboratory analysis techniques such as ELISA, SDS-PAGE, western blotting, qPCR, flow cytometry (essential to be confident in the use of some of these)
• Prior experience in bacterial cloning (desired)

The Package

As an up-and-coming Cambridge Biotech, our client is able to offer a competitive salary, progression options and benefits package including private pension.

To Apply

If you would like to apply to this opportunity, please send a copy of your CV to Charlie Cox at [e-mail] – alternatively, please call Charlie on 07903 204577.

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I'm interested in this job

Please use the form provided to get in touch with us and we will respond as soon as possible.

Compulsory fields are in bold.

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