3D Cell Morphology in Cancer Spatial Modelling

THE FRANCIS CRICK INSTITUTE LIMITED; Greater London; On-site; GBP 23,000 - 29,000; Full time

Job summary

The Francis Crick Institute Limited invites applicants for a 2027 Crick PhD project led by Josh Bull in Bull Lab. It focuses on computational modelling of cell morphology within the spatial organisation of cancer, using agent-based models to simulate how cell shape and movement emerge from microenvironmental cues in 3D tissues.

The successful student will extend a scalable simulation framework, apply mathematical modelling to tumour-immune interactions, and analyse cutting-edge imaging data to

Qualifications

• Strong coding background with Python, Rust or C++.
• Quantitative background in maths/CS/physics.
• Interest in applying quantitative skills to problems in cancer biology.

Responsibilities

• Develop and extend ABM framework for 3D tissue simulations.
• Model the role of cellular morphology in cancer spatial biology.
• Analyse imaging data and perform mathematical modelling.

Skills

Python

C++

Rust

Computational modelling

Education

Mathematics/CS/Physics degree

Tools

ABM frameworks

3D simulation

Job description

The Francis Crick Institute Limited invites applicants for a 2027 Crick PhD project led by Josh Bull in Bull Lab. It focuses on computational modelling of cell morphology within the spatial organisation of cancer, using agent-based models to simulate how cell shape and movement emerge from microenvironmental cues in 3D tissues.

The successful student will extend a scalable simulation framework, apply mathematical modelling to tumour-immune interactions, and analyse cutting-edge imaging data to