Toxicologist Study Director (F / H / NB)

Bayer; Grasse; Sur place; EUR 60 000 - 80 000; Plein temps

Résumé du poste

Une entreprise internationale dans la santé et l'agriculture recherche un Directeur d'Étude en Toxicologie à Sophia Antipolis. Vous serez responsable de la conduite globale des études toxicologiques, garantissant leur conformité avec les principes de bonne pratique de laboratoire. Ce poste exige un PhD en Toxicologie ou une expérience significative dans le domaine. Vous contribuerez au développement de protocoles expérimentaux et à la gestion de projets de recherche tout en respectant les lignes directrices internationales.

Prestations

Opportunités de carrière variées

Environnement de travail dynamique

Qualifications

• Niveau d'éducation élevé en Toxicologie ou sciences connexes.
• Minimum 7 ans d'expérience réussie dans le domaine.
• Capacité à conduire des projets scientifiques utilisant des animaux (Directive 2010 / 63 / UE).

Responsabilités

• Assurer la conduite d'études toxicologiques in-vitro et in-vivo.
• Définir les objectifs et le déroulement de l'étude dans un plan d'étude.
• Coordonner toutes les phases de l'étude avec d'autres scientifiques.

Connaissances

Gestion de projets scientifiques

Compétences en communication

Résolution de problèmes

Connaissance des lignes directrices réglementaires internationales

Compétences managériales

Anglais (écrit et oral)

Formation

PhD / Doctorat en Toxicologie ou sciences connexes

Description du poste

Toxicologist Study Director (F / H / NB)

Study Director in Toxicology (F / H / NB)

Study Director in Toxicology

• Be the single point of study control with ultimate responsibility for the overall conduct of the study and the compliance of the study and its final report with the French and OECD Principles of Good Laboratory Practice and international regulatory guidelines (when applicable).
• Be responsible for study plan design and approval, as well as overseeing data collection, analysis and reporting.
• Ensure that the scientific, administrative and regulatory aspects of the study are controlled and assume responsibility for the fidelity and validity of the data and the degree of compliance with GLP.
• As principal investigator, ensure that the delegated phases of the study are conducted according to the Quality Management System and applicable Principles of Good Laboratory Practice if applicable.

Your roles and responsibilities

• Act as Study Director for in-vitro and in-vivo toxicological studies ensuring the use of appropriate standard operating procedure according to the Quality Management System, the respect of all appropriate international regulatory guidelines and in accordance with GLP principles as described in the French Environment Code (Article Annexe II à l'article D523-8) on a range of different study types.
• Define the objectives and the whole conduct of the study and how they are to be achieved in a study plan and subsequent amendments that should make available to all personnel involved including quality assurance staff before the starting date.
• Ensure that the study plan and the final report for a multi-site study identify and define the role of any Principal Investigator(s) and any test facilities and test sites involved in the conduct of the study and coordinate all phases.
• Coordinate with other study scientists, and / or Principal Investigator(s) all phases of the study and drawing the final overall conclusions from the study.
• Ensure that the procedures, guidelines or regulatory documents specified in the study plan are followed and assess and document the impact of any deviations from the study plan on the quality and integrity of the study, and take appropriate corrective action if necessary; acknowledge deviations from Standard Operating Procedures during the conduct of the study.
• Ensure that all raw data generated are fully documented and recorded.
• Ensure that computerized systems used in the study have been validated.
• Sign and date the final report to indicate acceptance of responsibility for the validity of the data and to indicate the extent to which the study complies with these Principles of Good Laboratory Practice.
• Ensure that after completion (including termination) of the study, the study plan, the final report, raw data and supporting material are archived.
• Request and coordinate resources provided by management, such as personnel, equipment and facilities, to ensure they are adequate and available as scheduled for the proper conduct of the study.

Toxicologist

• Contribute to the development of new experimental protocols or new methods related to chemical families or client requirements.
• Ensure and promote an ethical, humane and responsible use of animals in accordance with the European directive 2010 / 63 / UE and the French Decree No. 2013-118 of February 1, 2013 relating to the protection of animals used for scientific purposes.
• As part of the scientific programs developed, manage research projects including the follow up of studies, budgets, communication of results, reports and costs, within the negotiated deadlines and coordinate research activities with external laboratories.
• Actively contribute to international working groups to advance best practices in toxicology, fostering collaboration and driving innovation in global safety standards.
• Challenge the status quo by proactively advocating for the adoption of innovative tools in toxicology, including data digitalization and automated reporting, to enhance efficiency and modernize toxicology practices.

Added value

The results of these studies are the basis for input into decisions regarding promotion or stopping of compounds, resolution of critical issues on compounds, and supporting the products of Bayer Crop Science Division in both the regulatory and public arena.

Your profile

High level of education in Toxicology or a closely related science (PhD / Doctorate) or at least 7 years of successful experience in the field.

Ability to conduct scientific project using animals (Directive 2010 / 63 / EU) : Level 1 / B.

Knowledge and use of English (written and oral).

Managerial skills : Ability to manage and motivate team work on routine / research projects.

Strength in communication and problem solving.

Knowledge of international regulatory guidelines and GLP principles.

Contract : permanent

Location : Sophia Antipolis (06) - FR

Qui sommes-nous ?

Bayer est un groupe international dont les cœurs de métier se situent dans les secteurs de la santé et de l’agriculture. A la confluence de la chimie et de la biologie, Bayer contribue à améliorer la qualité de vie en proposant des produits et services en santé humaine et végétale.

Chez Bayer nous sommes chaque jour motivés par les grands défis de notre époque. Notre ambition est de contribuer à un monde où la santé pour tous, la faim pour personne ne soient plus un rêve mais une possibilité, en protégeant chacun au quotidien. Dynamisme, curiosité et engagement guident nos actions. Nous pensons que nous pouvons apprendre de tous ceux qui nous entourent, en élargissant nos points de vue, en développant nos compétences, en faisant évoluer le statu quo. Il y a tellement de raisons de nous rejoindre. Vous avez envie d’une carrière riche de sens et qui offre des opportunités variées ? Vous souhaitez rejoindre des équipes expertes et diverses qui permettent le changement ? Le choix est simple !

«Pour Bayer, l’égalité des chances est un axe majeur de la responsabilité sociétale de l’entreprise

Code de référence : 857848