Research Engineer Process Development (F/M)

EDU Passport LLC; France; Hybride; EUR 40 000 - 60 000; Plein temps

Avantages offerts par ce poste

Company cafeteria

70% transport pass coverage

Company health insurance

Résumé du poste

The Curie Institute, Saint-Cloud, is seeking a Laboratory Scientist to join the CellAction manufacturing team focusing on cell and gene therapies. You will develop and optimize pre-GMP processes and ensure translational feasibility under GMP guidelines.

Ideal candidates hold a Master’s or PhD in biotechnology and have 2–5 years in process development, with experience in aseptic mammalian cell culture and gene editing. This full-time, fixed-term contract runs 12 months, with renewal options.

Qualifications

• Master’s degree or PhD in Biotechnology or related field
• 2–5 years of experience in process development (cell therapy, gene therapy, or drug development)
• Experience in aseptic mammalian cell culture, with preference for primary T-cell culture and cell expansion systems
• Knowledge of analytical characterization and CQAs for cell and gene therapy products, including titer, purity, potency, and sterility
• Hands-on experience with site-specific gene-editing technologies (CRISPR-Cas) desirable

Responsabilités

• Develop and optimize manufacturing processes for cell and gene therapies, including viral/non-viral vectors and genome editing
• Transfer pre-GMP processes into robust, reproducible workflows for clinical manufacturing
• Develop analytical methods and monitor CPPs and CQAs to ensure product quality
• Collaborate with multidisciplinary teams, troubleshoot, and support continuous process improvement
• Prepare technical documentation and ensure GMP and regulatory compliance
• Identify innovative approaches to improve process efficiency and maintain technology watch in the field

Connaissances

Aseptic culture

T-cell culture

Flow cytometry

CRISPR-Cas

Formation

Master’s degree in Biotechnology

PhD in Biotech

Description du poste

Job Location

Global

Job Description

Offer Description

Host Institution The Curie Institute Research Center The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Job description Laboratory - CellAction CellAction is part of Institut Curie’s commitment to building unique expertise in cell and gene therapy. It integrates multidisciplinary competencies in bioinformatics, target discovery and validation, molecular biology, genome editing, viral and non-viral vector design, cell engineering, and the development of in vitro and in vivo tumor models for cell and gene therapy applications.

Furthermore, CellAction provides pre-GMP process development expertise, aiming to generate fully characterized, GMP-ready cell therapy products that can be manufactured in dedicated GMP facilities and subsequently evaluated in clinical settings. In 2025, CellAction was permanently established at the Saint-Cloud site of Institut Curie.

At the Process Development group at CellAction, our activities focus on the development and optimization of manufacturing processes for cell- and gene-based therapies, ensuring translational feasibility and compliance with regulatory standards for clinical-grade production. https://curie. fr/cellaction-un-laboratoire-unique-pour-lacces-aux-therapies-cellulaires-et-geniques Missions / Responsibilities Develop and optimize manufacturing processes for cell and gene therapies, including viral/non-viral vectors and genome editing.

Transfer pre-GMP processes into robust, reproducible workflows suitable for clinical manufacturing. Develop analytical methods and monitor critical process parameters (CPPs) and critical quality attributes (CQAs) to ensure product quality. Collaborate with multidisciplinary teams, contribute to troubleshooting, and support continuous process improvement. Prepare technical documentation and ensure compliance with GMP and regulatory requirements.

Identify innovative approaches to improve process efficiency and maintain technology watch in the field of cell and gene therapy.

What We Offer Opportunity to work on cutting-edge therapies Dynamic and collaborative environment Competitive salary and benefits package Career development opportunities Profile and Qualification Basic Qualifications Master’s degree or PhD in Biotechnology, Biochemical Engineering, or related field 2–5 years of experience in process development (cell therapy, gene therapy, or drug development) Preferred Qualifications Demonstrated proficiency in aseptic mammalian cell culture, with preference for experience in primary T-cell culture, cell activation, and cell expansion systems (flasks, bags, or bioreactors), viral transduction techniques, immunophenotyping (e. g. Flow cytometry) Knowledge of analytical characterization and critical quality attributes (CQAs), preferably for cell and gene therapy drug products, including titer, purity, potency, and sterility. Hands‑on experience with site‑specific gene‑editing technologies (e. g. , CRISPR‑Cas) is desirable; however, it is not mandatory. Excellent written and verbal communication skills, with the ability to clearly present technical and scientific information to multidisciplinary teams.

Knowledge of GMP environment and regulatory expectations Strong analytical and problem‑solving skills Ability to work in a multidisciplinary and fast‑paced environment Fluent in English; French is a plus Required Skills and Competencies Ability to work independently in managing routine tasks Good communication skills Strong organizational skills Adaptability and responsiveness Ability to work effectively as part of a team All our opportunities are open to individuals with disabilities.

Contract Information Contract type: Fixed‑term contract (CDD) Start date: As soon as possible Contract duration: 12 months, renewable for an additional 12 months Working time: Full‑time – 39 hours per week Salary: According to current salary scales Benefits: Company cafeteria, 70% coverage of annual public transportation pass, company health insurance Location: Saint-Cloud Contact Please send your CV and cover letter : job-ref-qhatg37gb4@emploi. beetween.

Publication date: 25/09/2026 Deadline for application: once filled Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities. https://euraxess. ec. europa. eu/sites/default/files/brochures/eur_21620_en-fr. pdf