Research assistant

Centre de Recherche en Cancérologie de Marseille; France; Sur place; EUR 30 000 - 40 000; Plein temps

Résumé du poste

A leading cancer research center in France is seeking a motivated research assistant to support a project focused on developing new multispecific Chimeric Antigen Receptors. Key responsibilities include generating multi-specific CARs and evaluating CAR-T cell activity. Candidates should have a Master’s degree, strong immuno-oncology knowledge, and skills in protein engineering. This full-time position requires good proficiency in French and English.

Qualifications

• Strong knowledge of immuno-oncology and cell biology.
• Advanced skills in protein engineering, primary cell culture, cytometry, and microscopy.
• Ability to produce recombinant proteins in eukaryotic and prokaryotic systems.
• Ability to purify primary immune cells.

Responsabilités

• Generate multi-specific CARs for CAR-T cell activation.
• Evaluate the activity of CAR-T cells expressing these receptors in vitro.

Connaissances

Immuno-oncology knowledge

Cell biology

Protein engineering

Primary cell culture

Cytometry

Microscopy

Recombinant protein production

Primary immune cell purification

Formation

Master Degree or equivalent

Description du poste

Organisation/Company Centre de Recherche en Cancérologie de Marseille Research Field Biological sciences » Biology Researcher Profile Other Profession Positions Research Support Positions Country France Application Deadline 24 Dec 2025 - 14:34 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 38,5 Offer Starting Date 2 Feb 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

We are looking for a research assistant to work on a project dedicated to the development of new multispecific Chimeric Antigen Receptor. The Nanologic project aims to develop multispecific “all-in-one” CARs by concatenating “nanobodies” (Nb), single-domain specific molecules, in order to confer conditional activation to CAR-T cells with a single receptor. We hope to develop CAR receptors that will generate CAR-T cells with greater specificity for tumor cells and a greater ability to eliminate them.

The main responsibilities of the candidate for the position of research assistant will be :

• to generate multi‑specific CARs incorporating specific domains derived from camelid single chain antibodies (for conditional activation of the “OR” and “AND” gates).
• To evaluate the activity of CAR‑T cells expressing these receptors in vitro.

Where to apply

E‑mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level Master Degree or equivalent

Skills/Qualifications

• Strong knowledge of immuno‑oncology and cell biology.
• Advanced skills in protein engineering, primary cell culture, cytometry, and microscopy.
• Ability to produce recombinant proteins in eukaryotic and prokaryotic systems.
• Ability to purify primary immune cells.

Specific Requirements

• Scientific rigor and autonomy.
• Team spirit, ability to collaborate with different teams.
• Intellectual curiosity and ability to solve problems creatively.
• Effective organization and time management for complex projects.

Languages FRENCH Level Good

Languages ENGLISH Level Good

Research Field Biological sciences » Biology Years of Research Experience 1 - 4

Additional Information

Selection process

We are seeking highly motivated candidates to join our team.

To apply, please submit your application via email. Your application must include the following:

• The email address of a professional reference

Shortlisted candidates will be contacted for an interview as part of the final selection process.