R&D Project Leader - Cancer Cell Vulnerabilities

Servier France; Gif-sur-Yvette; Sur place; EUR 120 000 - 160 000; Plein temps

Résumé du poste

Servier France recherche un Project Leader – Cancer Cell Vulnerabilities pour rejoindre l’équipe Oncologie sur le site Paris-Saclay. Vous serez l’architecte scientifique et stratégique des programmes de découverte clinique, guidant les projets de l’idée initiale jusqu’à la nomination PCC.

Le rôle nécessite un PhD et 7–10+ années d’expérience en découverte oncologique de petites molécules, avec une forte capacité à diriger des équipes transverses et à influencer les décisions stratégiques.

Qualifications

• Docteur en biologie du cancer ou domaine connexe et expérience en découverte de petites molécules.
• Expérience avérée en leadership dans des programmes de découverte multi‑fonctionnels.
• Maîtrise de l’anglais (écrit et oral) requise pour un environnement international.

Responsabilités

• Diriger les programmes de découverte oncologique allant de l’identification à la nomination PCC.
• Définir la stratégie scientifique et translationnelle, et assurer l’exécution dans le respect des délais.
• Animer le Core Team et coordonner les expertises biologie, chimie, DMPK et biomarqueurs.
• Conduire les décisions Go/No-Go et gérer les risques scientifiques.

Connaissances

Leadership

Cross-functional leadership

Project management

English fluency

Formation

PhD in Cancer Biology or related

Description du poste

Date de parution: 7 sept. 2026

Ville: GIF-SUR-YVETTE

Pays/Région: FR

Type de contrat: CDI

N° offre: 12038

R&D Project Leader - Cancer Cell Vulnerabilities

We are a human-scale, international, and independent pharmaceutical group governed by a Foundation. Our unique model makes us proud and, more importantly, enables us to fully serve our mission: "Committed to therapeutic progress for the benefit of patients."\

As a global leader in cardiology, we aim to become a focused and innovative player in oncology by 2030, targeting hard-to-treat cancers and dedicating more than 70% of our R&D budget to this goal.

Who are we? 22,000 passionate individuals from over 50 nationalities, driven by an entrepreneurial spirit. Every day, we move forward with and for patients, with and for our teams, motivated by the desire to care, to dare, to grow, and to commit to being useful to those in need.

Come experience and contribute to our commitment #MovedByYou.

www.servier.com

Are you a strategic and visionary scientific leader passionate about transforming oncology drug discovery and identifying the next generation of cancer cell vulnerability treatments?

We are seeking a Project Leader – Cancer Cell Vulnerabilities to join our Oncology team at the Paris-Saclay site. This is a unique opportunity to act as the scientific and strategic architect of oncology drug discovery programs, driving projects from early concept to Preclinical Candidate (PCC) nomination. Your work will be pivotal and will directly impact the value created for patients within our therapeutic pipeline.

Why Join Us?

• Impactful Research: As a Project Leader, you are accountable for driving projects and providing the leadership required to turn scientific concepts into life-changing medicinal compounds.


• Innovative Environment: Work at the forefront of oncology innovation in Saclay. You will lead cross-functional teams using data-driven decision-making and have the opportunity to integrate emerging technologies, including AI-enabled approaches, to accelerate the discovery of small molecule therapeutics.


• Collaborative Team: Join a multidisciplinary and international matrix environment. You will chair the Core Team and act as the primary integrator across biology, medicinal chemistry, DMPK, and translational sciences ensuring a seamless transition from discovery to clinical development.

Responsibilities:

• Lead oncology discovery programs from target identification and validation through to PCC nomination with accountability for project strategy, scientific excellence, timelines, and quality of execution.


• Define and drive the scientific and translational strategy, including mechanism of action, clinical hypotheses, and patient stratification.


• Chair and lead the cross-functional Core Team, orchestrating scientific ambition with operational execution in partnership with Project Management.


• Drive scientific recommendations, Go/No-Go proposals, and risk-based decision-making within the governance framework


• Integrate diverse expertise across biology, pharmacology, chemistry, DMPK, biomarkers, and IP to ensure project coherence.


• Lead the design of mechanistic and pharmacology studies supporting clinical relevance.


• Engage and align internal stakeholders.


• Contribute to external opportunity assessment and represent the company in external scientific interactions.


• Mentor junior scientists and promote a culture of scientific excellence, innovation, and urgency.

Profile:

• Ph.D. (or equivalent) in Cancer Biology, Cell or Molecular Biology, Pharmacology, or a related discipline.


• 7–10+ years of experience in oncology small molecule drug discovery within a pharma or biotech environment.


• Proven track record of successfully leading cross-functional discovery programs from target validation to PCC nomination.


• Strong understanding of tumor biology, cancer vulnerabilities, translational research, and preclinical development.


• Demonstrated leadership in matrix organizations with excellent communication, influence, and collaboration skills.


• Highly organized approach with the ability to manage complex scientific risks and alternative scenarios.


• A proactive mindset with an interest in AI and digital tools as enablers of R&D acceleration.


• Fluency in English (oral and written) is mandatory for this international environment.

We are committed to equal opportunities and developing talents in all their diversity. We value both experience and the desire to engage daily in contributing to therapeutic progress for the benefit of patients. If this offer resonates with you, seize this opportunity to meet us!