Postdoctoral Researcher - H/F

Inserm France; Paris; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

A renowned French research institution in Paris is seeking a candidate to contribute to a project studying the role of macrophages in cardiac fibrosis. The role involves conducting experiments in animal models, managing transgenic mouse lines, and analyzing single-cell transcriptomics data. The ideal candidate should have a PhD, extensive experience in animal experimentation, and good skills in bioinformatics. This position offers the opportunity to work in an international team where English is the working language.

Qualifications

• Extensive experience in animal surgery for cardiovascular pathology models.
• Experience in preparing samples and single-cell RNA-seq libraries.
• Extensive experience in single-cell RNA-seq analysis and spatial transcriptomics.

Responsabilités

• Conducting and analysing single‑cell and spatial transcriptomics experiments.
• Management of transgenic mouse lines.
• Presenting results at international conferences.

Connaissances

Extensive experience in animal experimentation

Fluent spoken/written scientific English

Extensive experience in managing transgenic mouse lines

Extensive experience in flow cytometry

Scientific rigour and organisation

Ability to work in a team

Formation

PhD (Bac +8)

Outils

R

Python

Description du poste

Description

The successful candidate will work on an ANR‑funded project aimed at studying the role of macrophages in cardiac fibrosis using single‑cell and spatial transcriptomics methods.

Main activities

• Animal models of cardiovascular diseases (surgery)
• Management of transgenic mouse lines
• Conducting and analysing single‑cell and spatial transcriptomics experiments
• Presenting results at international conferences
• Preparing figures for scientific publications
• Writing scientific publications (in English)

Specific features and environment of the position

Emerging Inserm CPJ team within the Paris Centre for Cardiovascular Research‑Inserm U970, team of approximately 5 to 8 people.

International team, English is the working language for both spoken and written communication.

Profil recherché

Knowledge

• Cell biology
• Molecular biology
• Bioinformatics
• Cardiac pathophysiology
• Immunology, macrophage study models
• Cardio‑immunology
• Fluent spoken/written scientific English

Hard Skills

• Extensive experience in animal experimentation
• Extensive experience in animal surgery for cardiovascular pathology models
• Extensive experience in managing transgenic mouse lines
• Experience in preparing samples and single‑cell RNA‑seq libraries
• Extensive experience in single‑cell RNA‑seq analysis and spatial transcriptomics: analysis of multi‑omics single‑cell RNA‑seq data and spatial transcriptomics with R or Python bioinformatics packages, data integration, data mining, etc.
• Extensive experience in flow cytometry

Soft Skills

• Scientific rigour and organisation
• Autonomy
• Ability to work in a team

Desired experience

2 to 4 years post‑doctorate

Level of qualification and training

Bac +8