Postdoctoral position in molecular genetics and bioinformatics M/F

CNRS; France; Sur place; EUR 35 000 - 45 000; Plein temps

Résumé du poste

A research institution in France is offering a junior postdoctoral position focused on maintaining genome integrity during DNA replication. The role requires a PhD in genetics, expertise in yeast genetics, and bioinformatics skills. The successful candidate will perform quantitative analyses and develop bioinformatics pipelines at the Institute of Human Genetics in Montpellier.

Qualifications

• Demonstrates strong expertise in yeast genetics.
• Able to perform biological experiments (wet lab).
• Experience in analyzing sequencing data independently.

Responsabilités

• Use quantitative genome-wide approaches to determine RNA polymerase positions.
• Determine replication fork progression during S phase.
• Develop bioinformatics pipelines to analyze sequencing data.
• Generate graphical representations of results and present in meetings.

Connaissances

Yeast genetics

Bioinformatics

Quantitative genome-wide approaches

Data analysis

Formation

PhD in genetics

Description du poste

Organisation/Company CNRS Department Institut de Génétique Humaine Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Country France Application Deadline 9 Dec 2025 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

A junior postodoctoral position is opened (9 months) in the team "Maintenance of genome integrity during DNA replication" ; Institut de Génétique Humaine of Montpellier (https://www.igh.cnrs.fr/fr/recherche/departements/bases-moleculaires-de…). The project aims to identify how the S phase checkpoint limits transcription‑replication conflicts genome‑wide approaches in Saccharomyces cerevisiae.

The selected postdoctoral researcher will:

• use quantitative genome‑wide approaches to determine the position and amount of RNA polymerases by ChIP‑seq.
• use genome‑wide approaches to determine replication forks progression at different moments during S phase.
• develop and use appropriate bio‑informatic pipelines to analyse the obtained sequencing data.
• generate graphical representation of the main results and present them in meetings.

Selected applicant will work in the Institute of Human Genetics (IGH, CNRS, UMR9002) in Montpellier - France. Around 250 staff and students researchers work at the IGH in 24 groups. Main research areas include DNA replication and genome integrity and dynamics, developmental genetics and human pathalogies.

The successful candidate will join the "Maintaining Genome Integrity during Replication" team led by Philippe Pasero, which has around 18 members. More specifically, they will work on the "coordination of replication and transcription" project.

We are seeking for a highly motivated and autonomous junior postdoctoral researcher. Applicants must have a PhD in the field of genetics and demonstrate a strong expertise in yeast genetics, the use of genome‑wide approaches to analyse both transcription and replication. Applicants need to be able to perform biological experiments (wet lab) and to analyse sequencing data on their own (bioinformatics).