Postdoctoral Position – Cancer Immunology & Immunometabolism

iGRED; France; On-site; EUR 42,000 - 58,000; Full time

Job summary

iGReD Research in Clermont-Ferrand, France, invites applications for a Postdoctoral Researcher in Cancer Immunology within the MAVERIC project. The successful candidate will develop and characterize prostate cancer models, study dendritic-cell–mediated anti-tumor responses, and apply scRNA-seq and spatial transcriptomics with advanced data analysis.

The role offers an interdisciplinary environment, collaboration with chemists, and opportunities for publications and scientific leadership in

Qualifications

• Strong background in cancer immunology and tumor microenvironment.
• Expertise in dendritic cells.
• Experience in cell culture and (spectral) flow cytometry.
• Experience with animal models and relevant certification.
• Experience with scRNA-seq and/or spatial transcriptomics, including computational analysis.
• Independent, curious and collaborative.
• Good written and spoken English.

Responsibilities

• Develop and characterize genetically engineered and orthotopic prostate cancer models (CRISPR, lineage tracing, surgery).
• Investigate dendritic-cell and antitumor immune responses following LXR modulation and vaccination.
• Perform spectral cytometry, cell sorting, scRNA-seq and spatial transcriptomics, including downstream data analysis.
• Conduct cellular and molecular experiments using tumor and immune-cell models.
• Collaborate with chemists developing novel LXR ligands and with the multidisciplinary MAVERIC consortium.
• Contribute to publications, international conferences and dissemination of project findings.

Skills

cancer immunology

dendritic cells

cell culture

flow cytometry

spectral cytometry

animal models

French Level 1

scRNA-seq

spatial transcriptomics

computational analysis

independence

curiosity

collaborative mindset

English proficiency

Education

PhD or equivalent

Job description

Organisation/Company iGRED Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Application Deadline 19 Nov 2026 - 23:59 (Europe/Paris) Country France Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Jan 2027 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Projet : Microenvironment Metabolism-Adapted Vaccination for Enhanced Reactivation of Immunosurveillance in Advanced Prostate Cancer.

The NuReP team (Nuclear Receptors & Pathophysiology) at iGReD – Université Clermont Auvergne/CNRS/Inserm is seeking a highly motivated postdoctoral researcher to join the INCa-funded MAVERIC project.

The successful candidate will play a central role in the project and will:

• Develop and characterize genetically engineered and orthotopic prostate cancer models (CRISPR, lineage tracing, surgery).
• Investigate dendritic-cell and antitumor immune responses following LXR modulation and vaccination.
• Perform spectral cytometry, cell sorting, scRNA-seq and spatial transcriptomics, including downstream data analysis.
• Conduct cellular and molecular experiments using tumor and immune-cell models.
• Collaborate with chemists developing novel LXR ligands and with the multidisciplinary MAVERIC consortium.
• Contribute to publications, international conferences and dissemination of project findings.

Where to apply

E-mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent

Skills/Qualifications

• A strong background cancer immunology / tumor microenvironment; expertise in dendritic cells is a strong asset.
• Experience in cell culture and flow cytometry, ideally spectral cytometry.
• Experience with animal models and appropriate certification (French Level 1 or equivalent).
• Experience with scRNA-seq and/or spatial transcriptomics, including computational analysis.
• Scientific independence, curiosity and a strong collaborative mindset.
• Good written and spoken English.

Languages ENGLISH Level Good

Research Field Biological sciences » Biology Years of Research Experience 1 - 4

Additional Information

iGReD provides an interdisciplinary environment combining fundamental, translational and clinical research, with access to advanced platforms in genomics, cytometry, imaging and animal experimentation. The position offers strong training at the interface of cancer immunology, immunometabolism, preclinical oncology and single-cell/spatial omics, together with opportunities for scientific ownership, publications, international networking and development toward an independent academic, translational or biotechnology career. Located in central France, Clermont-Ferrand is a vibrant university city at the doorstep of the Chaîne des Puys and the Auvergne Volcanoes Regional Natural Park, offering outstanding opportunities for hiking, cycling and outdoor activities.