PhD Structural and Functional Charac. of a Novel Non-Specific Lipase Identified in Hazelnut

ESRF - The European Synchrotron; Grenoble; Sur place; EUR 25 000 - 32 000; Plein temps

Avantages offerts par ce poste

Relocation support

Résumé du poste

ESRF - The European Synchrotron in Grenoble invites applications for the NextSTEP Doctoral Programme. The project focuses on structural characterization of a hazelnut lipase using time-resolved crystallography, in collaboration with Turin and Ferrero.

Selected candidates must enroll in the University of Torino Doctoral School; the two-year contract is renewable for one year and relocation support is offered.

Qualifications

• Background in structural biology or protein biochemistry.
• Degree allowing enrolment for a PhD in chemistry, materials science, physics or related field.
• Diploma must be provided at some stage; official certificate may be issued for MSCA eligibility.
• Proficiency in English with proof at least at B2 level.

Responsabilités

• Join the NextSTEP Doctoral Programme at ESRF in Grenoble for a two-year contract, renewable.
• Enrolment in University of Torino / Doctoral School as a condition of recruitment.
• Research on lipase mechanism using biophysical and biochemical techniques, incl. time resolved crystallography.

Connaissances

Structural biology

Biochemistry

English proficiency

Formation

Master's degree or equivalent

Description du poste

Context & Job Description

Thesis subject: Structural and Functional Characterization of a Novel Non-Specific Lipase Identified in Hazelnut Seeds

You will join the multidisciplinary collaboration between the time resolved serial crystallography team at ID29, the Department of Science and Pharmaceutical Technology of the University of Turin and Soremartec company part of Ferrero for the study of lipase mechanism that is responsible for hazelnut rancidity outset. The study will combine biophysical and biochemical techniques combined with time resolved crystallography to understand the biochemical mechanism.

Further Information May Be Obtained From

• Daniele de Sanctis (tel.: [phone], email: [e-mail])
• Salvatore Adinolfi (tel.: [phone], email: [e-mail])

Expected profile

• A background in structural biology or protein biochemistry is desirable.
• Degree allowing enrolment for a PhD (such as MSc, Master 2 de Recherche, Laurea or equivalent) in chemistry, materials science, physics or a closely related science. However minimum degree level may vary between universities.
• The candidate must have obtained and provide proof of a diploma at the time of application. The European Commission/MSCA may consider a student eligible provided that the university issues an official certificate confirming that the degree has been completed. The diploma will have to be provided at a later stage and is a mandatory requirement for enrolment in a doctoral school.
• Proficiency in English (A proof of upper-intermediate B2 level must be included in the application. Applicants originating from native-English-speaking countries can apply without the need for proof of level. An official degree conducted in English will be also accepted as a proof). If the applicant is unable to provide proof, an English test (free of charge) will be requested.
• Compliance with the Marie Sklodowska-Curie mobility rule: candidates may not have resided or carried out their main activity (work, studies, etc.) in the host institute’s country for more than twelve months in the three years immediately before the application deadline (21/08/2026).
• All researchers recruited must be doctoral candidates, i.e. not already working towards or in possession of a doctoral degree at the date of the recruitment.
• Candidates must satisfy the conditions for enrolment in a doctoral programme.

Working conditions

You shall be enrolled in University of Torino / Doctoral School as a condition of your recruitment.

Contract of two years, renewable for one year.

What We Offer

• Join an innovative international research institute, with a workforce from 38 different countries
• Collaborate with global experts to advance science and address societal challenges
• Come and live in a vibrant city, in the heart of the Alps, and Europe's Green Capital 2022
• Enjoy a workplace designed to support your quality of life
• Benefit from our competitive compensation and allowances package, including financial support for your relocation to Grenoble

For further information on employment terms and conditions, please refer to https://www.esrf.fr/home/Jobs/what-we-offer.html

The ESRF is an equal opportunity employer and encourages applications from disabled persons.

Company Description

More details about the Nextstep Doctoral Programme on www.nextstep-programme.eu

NEXTSTEP will train 36 enthusiastic researchers to exploit the unique and transversal capabilities of analytical research infrastructures in tackling the challenges associated with sustainable development and industrial competitiveness in the areas of “Health”, “Digital, Industry & Space”, “Climate, Energy and Mobility” and “Food, Bioeconomy, Natural Resources, Agriculture and Environment”, which are at the heart of Horizon Europe. Host laboratories: ESRF and ILL (France), FZJ (Germany), AREA (Italy), NTNU (Norway).