Lead Formulation Scientist: Early Drug Profiling

1000scholars; Gif-sur-Yvette; Remote; EUR 90,000 - 120,000; Full time

Job summary

1000scholars is seeking a Senior Scientist in Early Formulation and Drug Profiling in Gif-sur-Yvette, France. The role leads drug delivery innovation, coordinates non-clinical formulation activities, and advances developability assessments to support clinical development.

You will plan and supervise laboratory work, apply new technologies including AI-driven predictions, and collaborate with DMPK, Translational Medicine, and CMC teams to ensure timely progression of portfolio projects.

Qualifications

• PhD in Pharmaceutical Technology or related field with 8–10 years in formulation and targeted drug delivery.
• Expertise with poorly soluble/poorly permeable molecules and oral bioavailability optimization.
• Strong knowledge of physicochemical characterization (XRD, DSC, particle size) and PBPK/AI tools.

Responsibilities

• Design and oversee formulation strategies for complex, poorly soluble or poorly permeable molecules to maximize in vivo exposure and oral bioavailability.
• Lead developability assessments of New Chemical Entities (NCEs).
• Identify and implement advanced targeted drug delivery technologies, including blood-brain barrier strategies.
• Collaborate with interdisciplinary project teams to ensure data alignment and resolve complex problems.
• Summarize results, monitor scientific and regulatory developments, and mentor colleagues.

Skills

Formulation strategy

Developability assessment

Drug delivery

Physicochemical characterization

AI predictions

PBPK modeling

Solubilization techniques

Project leadership

Mentoring

Cross-functional collaboration

Education

PhD in Pharmaceutical Technology

Tools

X-ray diffraction

DSC

Laser particle size analysis

µDissolution

PBPK modeling software

AI prediction models

Job description

1000scholars is seeking a Senior Scientist in Early Formulation and Drug Profiling in Gif-sur-Yvette, France. The role leads drug delivery innovation, coordinates non-clinical formulation activities, and advances developability assessments to support clinical development.

You will plan and supervise laboratory work, apply new technologies including AI-driven predictions, and collaborate with DMPK, Translational Medicine, and CMC teams to ensure timely progression of portfolio projects.