Laboratory technician

Orakl Oncology; Villejuif; On-site; EUR 32,000 - 46,000; Full time

Job summary

Orakl Oncology seeks a dynamic Lab Technician to execute large-scale drug screening on our semi-automated platform, handling PDOs for internal and external projects. You will contribute to expanding the biobank with patient-derived materials and help optimize 3D culture and screening processes.

You will maintain rigorous lab documentation, ensure aseptic technique, and collaborate with biology, ML, and research teams in a fast-growing biotech environment.

Qualifications

• BSc (or equivalent) in cellular biology, biotechnology or related field.
• Hands-on experience with mammalian cell culture and organoid-related work.
• Experience with drug screening assays or viability assessments.
• Strong attention to detail, organisational rigour and teamwork.
• Fluent in English and able to collaborate in an international team.

Responsibilities

• Actively participate in commercial contracts by handling PDOs and performing drug screening assays to generate robust datasets.
• Contribute to expanding the Orakl biobank with patient specimens and organoid cell lines.
• Improve automation and accelerate workflows in 3D cell culture and drug screening experiments.
• Maintain laboratory operations, documentation, and traceability, anticipating consumables and reagent needs.

Skills

Mammalian cell culture

3D cell culture

Drug screening assays

Attention to detail

Teamwork

English communication

Cancer biology curiosity

Colaboration and communication

Education

BSc in cellular biology/biotechnology or related

Job description

About Orakl Oncology

At Orakl Oncology, we are accelerating the development of oncology treatments. Today, fewer than 5% of new cancer drugs succeed in clinical trials. Clearly, new methods are needed. We combine cutting-edge biology and AI to build the next generation of insight platforms with the world’s largest cohort of patient tumor avatars. These avatars fuel our AI-powered predictive engine, helping to anticipate clinical trial outcomes, validate therapies, and uncover new drug candidates. By generating multimodal, real-world data, we deliver insights that consistently outperform existing solutions.

Our mission is simple yet ambitious: to bring more effective treatments to patients who need them - and to make drug development smarter, faster, and more personalized. We collaborate with top hospitals, research institutes, and pharmaceutical companies worldwide. Backed by leading investors, we are a fast-growing, mission-driven startup at the intersection of science and technology.

The company is growing fast, and we are now seeking the best talents to come and join our exciting and ambitious team in the fight against cancer - join us!

Position overview

Orakl Oncology works on a large cohort of patient-derived organoids (PDO) to predict clinical outcomes of patients and derisk clinical trials. We are looking for a dynamic and motivated Lab Technician to help us execute large-scale drug screening assays on our semi-automated platform, either for internal or external projects. In this position, you will:

• Actively participate in our commercial contracts: you will take care of numerous PDOs of interest and perform drug screening assays to generate high-quality, robust datasets. These results will be leveraged by our data science and computational biology teams to deliver actionable insights and decision-support data to our partners.
• Work on the expansion of the Orakl biobank: you will work on patient specimens and organoid cell lines to increase the amount of data collected, thus improving our understanding of cancer.
• Contribute to the optimisation procedures at Orakl: you will bring new ideas and approaches to improve automation and accelerate workflows in both 3D cell culture and drug screening experiments.
• Ensure smooth laboratory operations: you will play a key role in laboratory maintenance, documentation, and traceability of activities, while proactively anticipating the needs for consumables and reagents.

Required qualifications

• BSc (or equivalent degree such as BTS, BUT, Licence) in cellular biology, biotechnology or any related discipline.
• Hands‑on experience in mammalian cell culture, 3D cell culture and preferably organoid culture.
• Hands‑on experience in drug screening assays or viability assessment assay.
• Exceptional attention to detail and organisational rigour.
• Flexibility, and a taste for overcoming operational challenges.
• A genuine enthusiasm and passion for teamwork and learning.
• As part of an international team, ability to communicate clearly in English
• Genuine curiosity for cancer biology.
• Strong collaboration and communication skills to interact in an interdisciplinary setting with biologists, ML engineers and researchers.
• Previous experience working in cancer biology
• Fluent in English

Recruitment process

• HR Call (15 minutes call) – An initial discussion to better understand your background, experiences, and motivations.
• Technical Interview (45 minutes call) – A deep dive into your technical skills and expertise relevant to the role.
• Lab Case (Around 90 minutes) - You will be directly manipulating in our labs to demonstrate your ability to follow a specific protocol and to work under aseptic conditions.
• Founder Interview: As final step of our recruitment process, you will meet the CTO of Orakl Oncology in person at our office. This meeting is an opportunity for the founders to assess cultural fit and ensure alignment with our company values.

More about Orakl here and here