Job offer

Universite de Montpellier; France; Sur place; EUR 40 000 - 60 000; Plein temps

Résumé du poste

A leading academic institution in France is seeking a Post-Doc in organic chemistry for a 7-month temporary contract. The successful candidate will develop sustainable methodologies for synthesizing APIs using innovative chemical technologies. The role requires a PhD in medicinal or preparative organic chemistry, along with synthesis and analytical skills. The position offers a competitive salary between €2,200 and €2,270 per month, with responsibilities including synthesis development and collaboration on multidisciplinary research.

Qualifications

• Candidates must possess a PhD degree in a relevant field such as medicinal chemistry.
• Solid skills in synthesis and analytical methods are required.
• Experience in green chemistry and mechanochemistry is advantageous.

Responsabilités

• Develop sustainable methodologies for organic synthesis.
• Synthesize APIs or key intermediates and characterize them.
• Implement scalable and green routes for pharmaceutical processes.

Connaissances

Medicinal chemistry

Preparative organic chemistry

Synthesis methods (NMR, HPLC, MS, IR)

Green chemistry

Mechanochemistry

Reactive extrusion

Solid state characterization

Good communication skills

Formation

PhD in a relevant field

Outils

NMR

HPLC

MS

IR

Description du poste

Organisation/Company Universite de Montpellier Department Human Resources Research Field Chemistry » Organic chemistry Technology » Chemical technology Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Country France Application Deadline 9 Feb 2026 - 23:59 (Europe/Paris) Type of Contract Temporary Job Status Full-time Is the job funded through the EU Research Framework Programme? Horizon Europe Reference Number 2026-R0133 Is the Job related to staff position within a Research Infrastructure? No

Offer Description

- work environment: We are looking for a Post-Doc who wants to contribute to the allow successful delivery of APIs or key intermediates, by the use of novel technologies such as continuous flow mechanochemistry by reactive twin screw extrusion, identified by IUPAC as one of the ten top emerging technologies that will change the world. A unique opportunity for you to work in a scientific area of great importance, innovative and disruptive, in a setting at the interface with the industrial needs and in close interactions with excellent academic groups members of the European Programme Horizon IMPACTIVE (Innovative Mechanochemical Processes to synthesize ACTIVE pharmaceutical ingredients).

- main mission: The Post doc will work under the responsibility of Dr. Evelina Colacino, on the development of sustainable methodologies for organic synthesis, with a special attention to the preparation of value-added compounds for the pharmaceutical industry in large-scale by continuous flow mechanochemistry, mainly based on reactive twin screw extrusion and possibly by resonant acoustic mixing.

- activities: As a Post-Doc, you will deal with the synthesis and development of APIs or key intermediates, and their characterization (including at the solid state). Your main research objectives will be to propose and design straightforward access (meaning specifically route scouting) to APIs by reactive twin screw extrusion mainly (i.e. continuous flow mechanochemistry) and by resonant acoustic mixing possibly, at different scale, in alternative to solution-based procedures and to improve the ecological footprint of each synthesis at laboratory and large scales. The daily synthesis work will be performed at the Université de Montpellier (Charles Gerhardt Institute of Montpellier, ICGM) in France.

The research activity will mainly focus on:

• Design of scalable and green routes for APIs or key intermediates by reactive twin screw extrusion in alternative to solution-based processes currently used in the industry. Implementation of the process by resonant acoustic mixing could be considered, depending on the project needs.
• Investigation of the mechanochemical process parameters to access them at different scales;
• Green Chemistry metrics applied to the processes developed within the project;
• Solid state characterization of each APIs or key intermediates;
• Process development to access new pharmaceutical forms

The net monthly salary is between €2,200 and €2,270

The contract duration is 7 months

Where to apply

E-mail [e-mail]

Requirements

Research Field Chemistry » Organic chemistry Education Level PhD or equivalent

Research Field Technology » Chemical technology Education Level PhD or equivalent

Skills/Qualifications

To qualify for the position of Post-Doc, you must have a doctoral degree in a relevant field such as medicinal chemistry, preparative organic chemistry, with solid skills in synthesis and analytical methods (NMR, HPLC, MS, IR, etc.). Candidate should have a strong interest in the technological aspects of the project. Experience in green chemistry, mechanochemistry, reactive extrusion and solid state characterization is considered meritorious for this position, but not compulsory.

We are looking for you who can work independently but also in close collaboration with the group members and as a part of the European Programme Horizon IMPACTIVE. You can plan and organize your own work, take your own initiatives and responsibility, be analytical and creative and be able to deliver results in time. You also need to be able to report to the founders, hence, need good communication skills and an interest for multidisciplinary research.

To qualify for the position of Post-Doc, you must have a doctoral degree in a relevant field such as medicinal chemistry, preparative organic chemistry, with solid skills in synthesis and analytical methods (NMR, HPLC, MS, IR, etc.). Candidate should have a strong interest in the technological aspects of the project. Experience in green chemistry, mechanochemistry, reactive extrusion and solid state characterization is considered meritorious for this position, but not compulsory.

Additional Information

Work Location(s)

Number of offers available 1 Company/Institute Institut Charles Gerhardt Montpellier (ICGM) Country France Geofield