International PhD Fellowship Gene Regulation by RNA modifications

Rnaj; Grenoble; Sur place; Plein temps

Résumé du poste

A leading research institution in Grenoble is offering an International PhD Fellowship focusing on gene regulation by RNA modifications. This 3-year project, funded by the IDEX initiative, involves an interdisciplinary approach and collaboration with labs in Geneva. Ideal candidates are highly motivated students who have recently completed a Master's in Biology or related fields and have experience with Drosophila. Applications should include a motivation statement and CV.

Qualifications

• Candidates should be highly motivated and have a strong interest in gene regulation.
• Experience in Drosophila research is particularly encouraged.
• Applications should include a brief motivation statement and a CV.

Responsabilités

• Conduct research on RNA modifications and gene regulation.
• Collaborate internationally with research teams in Grenoble and Geneva.

Connaissances

Experience with Drosophila

Motivation and research interest in gene regulation

Solid understanding of biology

Formation

Master's degree in Biology or related areas

Description du poste

International PhD Fellowship Gene Regulation by RNA modifications

Created: 05 April 2019

Applications are invited from candidates interested in a PhD fellowship to study gene regulation by RNA modifications. This fellowship is funded by the IDEX initiative of University of Grenoble to promote international collaborations.

The N 6 -methyladenosine (m 6 A) mark is an abundant internal modification on RNAs and this is highly conserved from yeast to plants and animals. RNA methyltransferases ’write’ this mark on transcripts, and this can be ‘erased’ by demethylases, making it a dynamic regulatory modification. Proteins that can recognize the mark ‘read’ this signal on messages to impact RNA stability, translation, splicing and export. This project aims to use Drosophila as the main model to investigate the in vivo relevance of this mark in physiological processes. This interdisciplinary project will also make use of protein biochemistry, cell biology and computational methods.

One unique aspect of this 3-year PhD project is its strong international dimension. It will be a collaboration between the labs of Dr. Marie-Odile Fauvarque (University of Grenoble) and Dr. Ramesh Pillai (University of Geneva). The student will enroll for PhD at the University of Grenoble, France.

Highly motivated students who have recently completed their Masters in Biology or related areas, are invited to apply. Candidates with prior experience in working with Drosophila as a model are particularly encouraged. Applications should contain a brief motivation statement (300 words max) and a CV.