Intern: Lipid Nanoparticle MD & SAXS Insights

Laboratoire CP2M (CNRS/UCBL/CPE Lyon). UMR 5128; Villeurbanne; Sur place; EUR 12 000 - 17 000; Temps partiel

Résumé du poste

Laboratoire CP2M (CNRS/UCBL/CPE Lyon). UMR 5128 in Villeurbanne invites applications for an M2 internship on Molecular Dynamics Simulation of Lipid Nanoparticles. You will work under Fabrice Brunel and Giovanna Lollo on SAXS and MD simulations to model lipid systems.

The project aims to develop coarse-grained lipid and RNA models using MARTINI to analyze SAXS curves and assemble insights. Candidates should be pursuing a Master 2 in Polymer Chemistry, Macromolecular Chemistry, Materials

Qualifications

• Master’s Year 2 degree in Polymer Chemistry, Macromolecular Chemistry, Materials Chemistry, or a related field.
• Experience with Linux, Bash, and Python for data analysis.
• Basic knowledge of molecular dynamics and MD simulation software.
• Familiarity with soft-matter chemistry and lipid membranes.
• Strong problem-solving and communication skills.
• Interest in interdisciplinary research.

Responsabilités

• Parametrize specific ionizable lipids and RNA.
• Measure lipid membrane thickness and scattering length density profiles.
• Assess lipid membrane rigidity through lipid pulling and real-space fluctuation analysis.

Connaissances

Linux

bash

Python

MD simulations

GROMACS

soft-matter chemistry

problem-solving

communication

Formation

Master’s Year 2 degree in Polymer Chemistry

Outils

GROMACS

Description du poste

Laboratoire CP2M (CNRS/UCBL/CPE Lyon). UMR 5128 in Villeurbanne invites applications for an M2 internship on Molecular Dynamics Simulation of Lipid Nanoparticles. You will work under Fabrice Brunel and Giovanna Lollo on SAXS and MD simulations to model lipid systems.

The project aims to develop coarse-grained lipid and RNA models using MARTINI to analyze SAXS curves and assemble insights. Candidates should be pursuing a Master 2 in Polymer Chemistry, Macromolecular Chemistry, Materials