Generative AI and Multi-Agent Systems Research Engineer (M/F)

Institut Curie - Research Center; France; Sur place; EUR 60 000 - 90 000; Plein temps

Avantages offerts par ce poste

Subsidized staff restaurant

Public transport reimbursement

Private health insurance

Hybrid work opportunities

Résumé du poste

Institut Curie - Research Center is seeking a Generative AI and Multi-Agent Systems Engineer to join the AGORA project. You will design agent-based architectures for biomedical applications, evaluate AI frameworks, and develop workflows that integrate RAG, bioinformatics tools, and ML models.

Collaboration with biologists, clinicians and data engineers will be essential, with opportunities for publications in oncology.

Qualifications

• PhD (or equivalent) in Computer Science, AI, ML, Bioinformatics, Computational Biology or related field.

Responsabilités

• Design and develop multi-agent architectures for biomedical applications.
• Evaluate and benchmark large language models and agentic AI frameworks.
• Develop workflows integrating multi-step reasoning, RAG, bioinformatics tools and ML models.
• Connect AI agents with biomedical knowledge bases, analysis pipelines, and HPC resources.
• Define evaluation protocols assessing explainability, robustness and reliability.
• Collaborate with biologists, clinicians, bioinformaticians and data engineers.
• Contribute to scientific publications and future AI research in oncology.

Connaissances

Generative AI

Agentic AI

Information retrieval

RAG Systems

Linux/Software development

Knowledge graphs

Formation

PhD or equivalent in CS/AI/Bioinformatics/Computational Biology

Outils

LangGraph/LangChain

CrewAI

MCP

Description du poste

Organisation/Company Institut Curie - Research Center Department Administration Research Field Medical sciences Cancer research Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 30 Nov 2026 - 08:00 (Europe/Paris) Country France Type of Contract Temporary Job Status Full-time Hours Per Week 39 Offer Starting Date 27 Aug 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Contexte

Institut Curie is recruiting a Research Engineer or Scientist in Artificial Intelligence to join the AGORA project (AGentic Orchestration for Research and Clinical Applications in Oncology).

The ambition of AGORA is to design and validate one of the first agentic AI platforms fully dedicated to biomedical research and precision oncology. The platform will be capable of exploring complex biological data, integrating the latest medical knowledge, assisting molecular interpretation, and generating novel research hypotheses. To achieve this goal, AGORA combines large language models (LLMs), biomedical knowledge bases, bioinformatics tools, multi-omics datasets, and clinical data into a unified reasoning framework.

The project brings together experts in artificial intelligence, machine learning, and data science, specialists in health data integration and governance, researchers in systems biology and mechanistic modelling, as well as oncologists actively involved in precision medicine programmes.

The successful candidate will work at the interface of these different groups and will join the Bioinformatics Core Facility and INSERM U1331 Computational Oncology Unit, a highly interdisciplinary environment comprising approximately 100 researchers working in computational biology, bioinformatics, and artificial intelligence.

The position is central to the project and aims to develop the scientific and technological foundations of a new generation of AI assistants for oncology.

As a Generative AI and Multi-Agent Systems Engineer (M/F), you will:

• Design and develop multi-agent architectures for biomedical applications.
• Evaluate and benchmark large language models and agentic AI frameworks.
• Develop workflows integrating:
  • multi-step reasoning,
  • Retrieval-Augmented Generation (RAG),
  • bioinformatics and biological modelling tools,
  • machine learning and predictive AI models.
• Connect AI agents with biomedical knowledge bases, analysis pipelines, and HPC resources.
• Define evaluation protocols assessing response quality, explainability, robustness, and reliability.
• Collaborate closely with biologists, clinicians, bioinformaticians, and data engineers.
• Contribute to scientific publications and future research projects in AI and precision oncology.

Candidate Profile

Education

• PhD (or equivalent experience) in Computer Science, Artificial Intelligence, Machine Learning, Bioinformatics, Computational Biology, or a related field.

Technical Skills

• Strong experience with generative AI and large language models.
• Experience with agentic AI systems or complex orchestration architectures.
• Good knowledge of information retrieval methods, RAG systems, vector databases, and/or knowledge graphs.
• Familiarity with Linux environments and modern software development practices.

Preferred Qualifications

• Experience with LangGraph/LangChain, CrewAI, MCP, or similar frameworks.
• Experience in biology, genomics, digital health, biomedical research, or oncology.
• Scientific publications in AI, machine learning, bioinformatics, or computational biology.

Personal Skills

• Scientific curiosity.
• Ability to work autonomously.
• Interest in interdisciplinary research.
• Ability to transform exploratory ideas into robust and reusable solutions.

Why Join Us?

AGORA offers a unique opportunity to help shape the next generation of AI systems for oncology by working on real-world scientific and clinical challenges alongside leading researchers and physicians.

The project brings together several of the most exciting areas of modern artificial intelligence, including large language models (LLMs), multi-agent systems, knowledge graphs, multi-omics data integration, biological modelling, and clinical decision support.

Beyond technology development, the ambition is to explore how agentic AI can become a genuine scientific partner - capable of reasoning over complex biomedical data, integrating up-to-date medical knowledge, supporting molecular interpretation, and generating novel research hypotheses.

At the intersection of fundamental research, data science, systems biology, and precision medicine, Institut Curie provides a world-class research environment with access to unique clinical and molecular datasets. You will work within a highly interdisciplinary team and benefit from significant scientific freedom, opportunities for high-impact publications, international collaborations, and participation in the development of future national and European research initiatives.

Contract Information

Starting date: As soon as possible

Duration: 18 months

Salary: According to experience and institutional salary scales

Benefits: Subsidized staff restaurant, public transportation reimbursement (70%), Private health insurance, Hybrid work opportunities

Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity.