Postdoctoral Position in the Intracellular Compartmentation

Centre for Genomic Regulation; Barcelona; Presencial; EUR 42.000 - 54.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Extended vacation period

Flexible working hours

Diversity and inclusion

Descripción de la vacante

The Centre for Genomic Regulation (CRG) in Barcelona invites applications for a Postdoctoral position focused on intracellular compartmentation and secretion mechanisms. The successful candidate will work on molecular cell biology, imaging, and Golgi function, with emphasis on TANGO1 and related pathways.

We seek a motivated scientist with a PhD, a strong publication record, and expertise in super resolution microscopy and genetic manipulation. Fluency in English is essential; Spanish is a plus.

Formación

• Must have a comprehensive understanding and proven ability to modern approaches of molecular cell biology, imaging, and genetic manipulation.
• Experience with super resolution microscopy and publications demonstrating expertise.
• Excellent written and verbal communication skills in English.

Responsabilidades

• Carry out molecular cell biology experiments and imaging studies.
• Design and execute projects related to intracellular compartmentation and secretion mechanisms.
• Publish results in high-impact journals and present findings at conferences.

Conocimientos

Molecular cell biology

Imaging

Genetic manipulation

Super resolution microscopy

Educación

PhD in a relevant field

Descripción del empleo

Postdoctoral Position in the Intracellular Compartmentation

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

We would like to hire a postdoctoral researcher passionate about science and willing to undertake challenging new projects with expertise in molecular cell biology, super resolution microscopy, and demonstrated record of publication in highly recognized journals.

The lab discovered TANGO1 as an endoplasmic reticulum exit site specific trans membrane protein which functions in secretion of vital proteins too big in size or secreted in huge quantities that cannot be trafficked by standard small vesicles. The aim is to address the mechanism by which TANGO1 functions in secretion of proteins such as mucins, collagens and insulin.

About the lab

The lab is interested in revealing the mechanism of protein secretion. Protein secretion is an old problem of fundamental interest and while a number of questions remain unsolved, we have focused on the following key questions.

• Mechanism of collagen secretion to address the issue of tissue fibrosis (collagenopathies).
• Mechanism of Mucin secretion and the associated pathologies of COPD and cystic fibrosis
• The mechanism of unconventional protein secretion.
• The shape and the biogenesis of functional Golgi cisternae.
• The biogenesis of transport carriers at the Golgi cisternae.

Whom would we like to hire?

Professional experience

Must Have

• Must have a comprehensive understanding and proven ability to modern approached of molecular cell biology, imaging, genetic
• All approaches of modern cell biology that included genetic manipulation of respective genes in metazoans, super resolution microscopy, and publications to demonstrate expertise in the procedures mentioned.
• Excellent written and verbal communication skills in English

Desirable but not required/ Nice to have

• Working knowledge of Spanish

Education and training

• PhD in a relevant field of study and completed within a well-established research environment

Languages

• Proficient in written and spoken English

Technical skills

• Fully fluent in techniques of molecular cell biology and super resolution microscopy

Competences

• Experimental approaches of cell biology
• Excellent organizational and time-management abilities
• A demonstrated ability to organize and contribute original ideas to scientific research.

The Offer – Working Conditions

• Contract duration: 3 years
• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
• Target start date: January 4, 2027

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Deadline: Please submit your application by 23/09/2026

Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form .