PhD position in the MSCA-DN “CanGoNano”

Universidad Internacional de La Rioja; Pozuelo de Alarcón; Sur place; EUR 28 000 - 35 000; Plein temps

Résumé du poste

Universidad Internacional de La Rioja (UNIR) in Spain is advertising a 36‑month MSCA Doctoral Network PhD position focused on glyconanomaterials for delivering peptide antigens or mRNA in breast cancer models. The role sits in Madrid and Logroño, joining leading groups in glycoscience, nanotechnology and cancer immunotherapy.

The selected candidate will be enrolled in a doctoral programme and receive structured training, international secondments and access to state‑of‑the‑art facilities through

Responsabilités

• Characterization and transfection of HER2 breast cancer cell lines.
• Set up doses of breast-transfected cell lines, kinetics of tumour progression and immune responses in vivo.
• Evaluate GNM formulations (with/without adjuvants) and doses to activate immune organs in vivo.
• Examine the capacity of GNM as breast cancer immunotherapies: prophylactic vs therapeutic effects.
• Training in GNM assembly & formulation, anti-cancer immunotherapy, establishing breast cancer in mice, bionanotech, biointeractions.

Description du poste

Host Institution

Universidad Internacional de La Rioja (UNIR), Spain https://www.unir.net

PhD Position in the MSCA Doctoral Network “CanGoNano” - Glyconanomaterials for the Delivery of Peptide Antigens or mRNA in Breast Cancer Models: Formulation and Anti-Cancer Efficacy

Offer Description

CanGoNano is a European Doctoral Network funded under the Horizon Europe Marie Skłodowska-Curie Actions – Doctoral Networks (MSCA-DN) programme. The network focuses on the development of glyconanomaterials (GNMs) as precision tools to advance our understanding of antigen‑presenting cell (APC) activation against cancer through the delivery of antigenic peptides and mRNAs encoding these peptides.

Within the CanGoNano consortium, the Universidad Internacional de La Rioja (UNIR) is recruiting one Doctoral Candidate (DC14) to undertake research on the development of glyconanomaterials for the delivery of peptide antigens or mRNA in breast cancer models. The candidate will be based in Madrid and Logroño (Spain) and will join the MEDONLINE Research Group at UNIR: https://investigacion.unir.net/grupos/35492/detalle and the Centro de Biología Molecular Severo Ochoa (CBMSO-UAM): https://www.uam.es/uam/investigacion/grupos-de-investigacion/detalle/f1-95

Research Project

• Characterization and transfection of HER2 breast cancer cell lines.
• Set up of the doses of breast‑transfected cell lines, kinetics of tumour progression and immune responses in vivo.
• Evaluation of GNM formulations (including or not adjuvants) and doses to activate immune organs in vivo.
• Examine the capacity of GNM as breast cancer immunotherapies: prophylactic vs therapeutic effects.
• Training in GNM assembly & formulation, anti‑cancer immunotherapy, establishing breast cancer in mice, bionanotech, biointeractions.

Duration

36 months, starting on 15 February 2027.

Supervisors

• Prof. Carmen Álvarez‑Domínguez, Universidad Internacional de La Rioja (UNIR), Spain (https://www.researchgate.net/profile/Carmen-Alvarez-Dominguez)
• Prof. Nuria Gironés Pujol, Universidad Autónoma de Madrid (UAM), Spain (https://www.researchgate.net/profile/Nuria-Girones)

Co‑supervisor

• Dr. Jürgen Mairhofer, EnGenes Biotech GmbH (Austria)

Planned Secondments

• CNRS (France) – Prof. Catherine Menard‑Moyon (Year 2, 1 month): training in the synthesis of amino acid‑based nanoparticles (AA‑NPs).
• EnGenes Biotech GmbH (Austria) – Dr. Jürgen Mairhofer (Year 3, 1 month): training in lectin expression technologies.

Doctoral Programme

The selected candidate will be enrolled in the PhD Programme in Molecular Biosciences at the Universidad Autónoma de Madrid (UAM), Spain. https://www.uam.es/EscuelaDoctorado/(en_GB)-Programa-Doctorado_Biociencias_Moleculares/1446833580304.htm

The Position Offers

• A 36‑month full‑time employment contract funded by the Marie Skłodowska‑Curie Actions – Doctoral Networks (MSCA‑DN) programme.
• Competitive salary and employment conditions in accordance with the MSCA regulations and the host institution's policies.
• Enrolment in the PhD Programme in Molecular Biosciences at the Universidad Autónoma de Madrid.
• Personalised scientific supervision by internationally recognised experts in glycoscience, nanotechnology and cancer immunotherapy.
• Access to state‑of‑the‑art research facilities and multidisciplinary expertise at UNIR, UAM and partner institutions.
• International mobility through planned secondments at leading European research organisations and biotechnology companies.
• A structured training programme covering both scientific and transferable skills, including innovation, communication, entrepreneurship, research management and career development.
• An inclusive, collaborative and multidisciplinary research environment committed to excellence in doctoral training.

Application

Further information about the CanGoNano Doctoral Network: https://euraxess.ec.europa.eu/jobs/448431 and the application process is available at: https://cangonano.eu/

EEO & Data Protection Statement

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