Technical System Manager for Statistical Programming

ASCENDIS PHARMA A/S; Gentofte Kommune; On-site; DKK 650,000 - 850,000; Full time

Job summary

ASCENDIS PHARMA A/S in Hellerup, Denmark, is seeking a Technical System Manager to design and implement technical solutions supporting Biometrics and Pharmacometrics. You will be responsible for ensuring system validation and inspection readiness, collaborating with teams to enhance technical capabilities, and maintaining vendor oversight.

The ideal candidate holds a Master's degree and has 5+ years of experience in Statistical Computing Environments within a pharmaceutical context. This role offers a dynamic work environment and significant impact on patient care.

Qualifications

• Solid experience with Statistical Computing Environments from a pharma context.
• 5+ years of relevant experience across complex organizations.
• Strong understanding of Biometrics and their systems.

Responsibilities

• Design and implement technical configuration and solutions to support Biometrics and Pharmacometrics.
• Translate criteria into specifications of configuration needed in our SaaS applications.
• Ensure systems are in a validated state and are inspection-ready.
• Prepare and present our systems and the related documentation during audits.

Skills

Statistical Computing Environments

Biometrics systems

Collaboration with SaaS vendors

Experience with GxP processes

Education

Master’s degree or equivalent technical role

Job description

Are you a technical system manager with deep understanding of statistical computing environments, biometrics process and data flows? Do you think holistically, act with ambition, and ensure the right functionality and system stability for biometrics?

Can you ensure great technical solutions, inspection-readiness and a great end‑user experience for biometrics users?

You may be our new Technical System Manager.

Ascendis Pharma is a global biopharmaceutical company committed to making a meaningful difference in patients’ lives. Guided by our core values of Patients, Science, and Passion, we are applying innovative TransCon® technology platform to fulfill our mission of developing new therapies that demonstrate best‑in‑class potential to address unmet medical needs.

At our headquarters in Hellerup, Denmark, we advance programs in our Endocrinology Rare Disease and Oncology portfolios. We also collaborate with partners on the development of TransCon‑based products in other therapeutic areas and markets.

Context

This position is based in our Global IT organization. In Global IT, we have built a product‑driven organization focused on product management and lifecycle thinking, where long‑lived teams take full ownership from problem discovery to solution delivery and continuous improvement.

Our structure combines clear leadership intent with empowered teams supported by People Leaders and Functional Leaders, fostering autonomy and self‑organization to enable fast flow, clear accountability, and minimal dependencies.

Within the Clinical domain, our organization consists of two product teams and a data team, supporting key areas including Clinical Operations, Clinical Development, Biometrics, Clinical Data Management, and Clinical Trial Supply.

Responsibilities

• Design and implement technical configuration and solutions to support Biometrics and Pharmacometrics
• Translate criteria into specifications of configuration needed in our SaaS applications
• Either implement the configurations yourself or work with the managed services provider or vendor to implement the configuration
• Ensure systems are in a validated state and are inspection‑ready
• Prepare and present our systems and the related documentation during audits and inspections
• Oversee system support and act as escalation point for tickets
• Maintain operational oversight over vendors
• Facilitate end‑user training and user groups
• Be visionary in improving our technical capabilities and suggest and implement improvements for automation, integration and seamless data flows
• Assist with documentation and validation of solutions
• Collaborate within and across the IT product teams when solving problems and delivering solutions

Qualifications and Experience

You hold a relevant academic degree – preferably a Master’s degree, with a background as an Engineer, System Manager or an equivalent technical role.

You have solid experience with Statistical Computing Environments from a pharma context and 5+ years of relevant experience across complex organizations.

• Strong understanding of Biometrics and their systems
• Technical knowledge of infrastructure components besides the application layer
• Experience working with SaaS vendors
• Experience with GxP processes for system management

Key Competencies

You are a strong team player, analytical, and have a can‑do attitude. You possess an entrepreneurial mindset and can thrive in an informal, open environment where innovation and change are key. You excel at collaborating with business in complex and ambiguous settings, handling conflicts constructively and helping groups move forward.

What We Offer

We offer an exciting and challenging position in an entrepreneurial and international company with short decision paths. You will work with highly skilled colleagues and play a key role in shaping how Global IT delivers sustainable value to Ascendis Pharma and, ultimately, to patients.

Travel: 10‑15 days per year

Office: Tuborg Boulevard 12, 2900 Hellerup

Flexibility: Some of the Biometrics organization is located in the US, and meetings in the afternoon and evening will occur

For more information about the position or the company, please contact Jakob Monajemzadeh Thrane, People Leader, [e-mail].