Senior Principal Scientist: Molecular Innovation & Discovery

Novo Nordisk; Måløv; On-site; DKK 847,000 - 1,245,000; Full time

Job summary

Novo Nordisk in Måløv, Denmark is seeking a Senior Principal Scientist to build an interdisciplinary Global Research team and translate biology into molecular interventions. You will shape early discovery and co-create therapeutic concepts for cardiometabolic disease and healthspan, leading design of molecules and pharmacological evaluation.

You will provide scientific leadership at the interface of molecular design, biology and pharmacology, mentor colleagues, and collaborate across disciplines

Qualifications

• PhD in a related discipline with at least eight years of post-PhD research experience; candidates from academia, biotech or pharma are eligible.
• Deep expertise in molecular design and understanding how molecular properties affect pharmacological activity.
• Experience connecting chemistry with biological assays and in vivo findings to guide molecular optimisation.
• Proven ability to lead scientific work and influence decisions across multidisciplinary collaborations.

Responsibilities

• Originate therapeutic concepts linking biology with opportunities for molecular intervention and design drug candidates.
• Develop strategies involving peptides, small molecules, conjugates or other modalities.
• Guide iterative molecular design using in vitro, in vivo pharmacology and DMPK findings.
• Contribute hands-on to experimental research such as molecular preparation and pharmacological evaluation.
• Identify technologies that expand ability to modulate targets or deliver activity.
• Assess evidence and recommend concepts to advance or discontinue.
• Mentor colleagues and communicate strategies and findings across disciplines.

Skills

Molecular design

Pharmacology

Biology assays

In vivo findings

Leadership in multidiscip

Scientific communication in English

Education

PhD in medicinal chemistry, chemical biology, molecular pharmacology, peptide chemistry or related discipline

≥8 years post-PhD research experience

Job description

Novo Nordisk in Måløv, Denmark is seeking a Senior Principal Scientist to build an interdisciplinary Global Research team and translate biology into molecular interventions. You will shape early discovery and co-create therapeutic concepts for cardiometabolic disease and healthspan, leading design of molecules and pharmacological evaluation.

You will provide scientific leadership at the interface of molecular design, biology and pharmacology, mentor colleagues, and collaborate across disciplines