Senior Clinical Trial Manager

Genmab; København; On-site; DKK 873,000 - 1,309,000; Full time

Benefits offered by this job

401(k) match

Health benefits

Parental leave

Wellness resources

Commuter benefits

Tuition reimbursement

Lifestyle Spending Account

Job summary

Genmab is seeking a Senior Clinical Trial Manager to lead global oncology trials with strategic oversight and operational excellence. You will work with Clinical Trial Teams, CROs, and investigators to ensure studies run on time, within budget, and in line with regulatory and Genmab’s quality expectations.

You will collaborate across global teams, drive risk management, and mentor colleagues in a matrixed environment. This role offers ownership and autonomy in a dynamic, science-driven setting.

Qualifications

• Bachelor’s degree in life sciences or related field; Master’s degree preferred.
• 8+ years of clinical trial management experience in pharma/biotech.
• Strong knowledge of ICH/GCP regulations and lifecycle.
• Experience managing global, multi-center trials in a matrixed organization.
• Excellent PM, vendor oversight, and cross-functional collaboration.
• Experience in oncology or specific therapeutic areas is desirable.
• Ability to lead without authority and mentor others in cross-functional settings.

Responsibilities

• Lead the operational planning, setup, and execution of global clinical trials, ensuring on-time delivery and compliance with standards.
• Oversee trial documentation, systems, accuracy, completeness, and inspection readiness.
• Drive site feasibility, selection, and activation strategies with CROs and internal stakeholders.
• Manage CROs and service providers to ensure high-quality deliverables and timely collaboration.
• Proactively identify, assess, and mitigate operational risks using risk-based quality management.
• Oversee protocol deviations, issue management, and escalation of trial-level challenges.
• Monitor trial performance and data quality using key metrics to drive improvements.
• Act as a cross-functional leader, fostering collaboration across teams, vendors, and investigators.

Skills

ICH/GCP knowledge

Global trial management

Project management

Vendor oversight

Communication

Collaboration

Oncology experience

Leadership

Education

Bachelor’s degree in life sciences

Master’s degree preferred

Job description

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

About The Role

At Genmab, we’re dedicated to developing and delivering innovative antibody-based therapeutics to improve the lives of patients. As a Senior Clinical Trial Manager (CTM), you will play a pivotal role in driving the success of our clinical trials through strategic oversight, operational excellence, and cross-functional collaboration.

The Senior CTM partners closely with Clinical Trial Teams (CTTs), service providers, and investigators to ensure that our clinical studies are executed on time, within budget, and in full compliance with regulatory standards and Genmab’s high-quality expectations. This role offers the opportunity to work in a dynamic, global, and matrixed environment where you will be empowered to take ownership and lead with autonomy.

Key Responsibilities

• Lead the operational planning, setup, and execution of global clinical trials, ensuring delivery on time, and in compliance with regulatory and quality standards.
• Oversee trial documentation and systems, ensuring accuracy, completeness, and continuous inspection readiness.
• Drive site feasibility, selection, and activation strategies in collaboration with CROs and internal stakeholders.
• Manage and oversee CROs and other service providers, ensuring high-quality deliverables, adherence to timelines, and effective collaboration.
• Proactively identify, assess, and mitigate operational risks using risk-based quality management approaches.
• Oversee protocol deviations, issue management, and ensure appropriate escalation and resolution of trial-level challenges.
• Monitor trial performance and data quality, leveraging key metrics to drive decision-making and continuous improvement.
• Act as a key cross-functional leader, fostering strong collaboration across internal teams, vendors, and investigators.

Qualifications

• Bachelor’s degree in life sciences or related field (Master’s degree preferred).
• 8+ years of experience in clinical trial management within the pharmaceutical or biotechnology industry.
• Solid understanding of ICH/GCP regulations and the clinical drug development lifecycle.
• Proven experience managing global, multi-center trials and working in a complex, matrixed organization.
• Strong project management and service provider oversight skills.
• Excellent communication, collaboration, and interpersonal skills.
• Oncology and/or therapeutic area–specific experience is highly desirable.
• Ability to lead without authority and mentor others in a cross-functional environment.

For US based candidates, the proposed salary band for this position is as follows:

$130,720.00---$196,080.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives.

When You Join Genmab, You’re Joining a Culture That Supports Your Physical, Financial, Social, And Emotional Wellness. Within The First Year, Regular Full-time U.S. Employees Are Eligible For

• 401(k) Plan: 100% match on the first 6% of contributions
• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

Further details on eligibility for compensation and benefits based on role will be provided during the recruitment process

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website Job Applicant Privacy Notice (genmab.com).

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.