Postdoc: Immunology & Fibrosis with 3D Skin Models

Aarhus University; Aarhus; On-site; DKK 420,000 - 540,000; Full time

Job summary

Aarhus University, Department of Biomedicine, invites applications for a two-year, full-time postdoctoral position in Immunology and Fibrosis. The role focuses on immune cell–fibroblast interactions in skin fibrosis and systemic sclerosis, using state-of-the-art multi-omics and in vitro/in vivo models.

English is the working language, and the candidate will contribute to research and teaching. The successful candidate will work in a diverse international team, supervisor support will be

Qualifications

• PhD in immunology, autoimmunity, molecular medicine, molecular biology, biomedical sciences or a related field.
• Experience with high-dimensional datasets, especially single-cell RNA sequencing or spatial transcriptomics.
• Experience in experimental immunology, particularly T-cell biology and inflammatory signaling.
• Advanced cell culture: primary human cells, immune cell isolation, and functional co-culture assays.
• Proficiency with multicolor flow cytometry, immunofluorescence microscopy, and gene/protein expression analyses.
• Development or application of advanced experimental models, including 3D cell cultures, organoids, or ex vivo tissue models, and animal/mouse models of inflammation or fibrosis.
• Fluency in oral and written English.

Responsibilities

• Independent research of high international quality, including publication.
• Analyzing and integrating multi-omics datasets, including single-cell and spatial transcriptomics, to identify cellular interactions and signaling pathways associated with fibrosis.
• Performing advanced cellular and molecular analyses, including multicolor flow cytometry, immunofluorescence, and gene expression profiling.
• Establishing and optimizing primary cell cultures and in vitro co-culture systems to investigate interactions between T cells and fibroblasts.
• Developing and applying 3D ex vivo skin models using patient-derived biopsies to investigate fibrotic mechanisms and evaluate potential therapeutic interventions.
• Contributing to experimental studies using mouse models of skin fibrosis, including bleomycin-induced fibrosis and keloid models.

Job description

Aarhus University, Department of Biomedicine, invites applications for a two-year, full-time postdoctoral position in Immunology and Fibrosis. The role focuses on immune cell–fibroblast interactions in skin fibrosis and systemic sclerosis, using state-of-the-art multi-omics and in vitro/in vivo models.

English is the working language, and the candidate will contribute to research and teaching. The successful candidate will work in a diverse international team, supervisor support will be