Bioprocessing Specialist, Fermentation and Production

Yngvi Bio; København; Hybrid; DKK 600,000 - 900,000; Full time

Job summary

Yngvi Bio ApS in Copenhagen seeks a hands-on, mid-level Bioprocessing Specialist to turn benchtop microbial fermentation into repeatable pilot production and to support transfers to manufacturing partners. The role supports material delivery for formulation, soil and field testing and suits someone with one or two completed scale-up cycles and a bench-to-production mindset.

You will directly perform development at the bench and in bioreactors, collaborate with scientists and quality teams, and

Qualifications

• 3-6 years in microbial fermentation, upstream bioprocess development or production-facing biotech.
• Hands-on fermentation experience: setting up, running, sampling and troubleshooting bioreactors.
• Experience with recombinant protein expression and linking process to yield, quality and recovery.

Responsibilities

• Plan and execute microbial batch and fed-batch fermentations with defined media, feed, induction, pH, DO, aeration and harvest strategies.
• Improve recombinant protein expression and solubility to optimize yield and product quality.
• Translate lab processes toward larger scales (50–1,000 L and beyond) and support transfer to manufacturing partners.
• Run repeatable, traceable batches supplying material for formulation, soil and field testing.
• Perform harvest, disruption or extraction and minimal purification for testing.
• Use structured experiments and data analysis to investigate deviations and ensure lot quality.
• Maintain SOPs, batch records and transfer documentation and collaborate with cross-functional teams.

Skills

Fermentation development

Protein expression

Scale-up

Quality control

Data analysis

Education

BSc / MSc / PhD in engineering or biotechnology

Tools

Bioreactors

HPLC

Job description

A hands-on, mid-level role turning benchtop microbial fermentation into repeatable pilot production, supporting transfer to manufacturing partners and delivering material for formulation, soil and field testing.

About Yngvi Bio

At Yngvi Bio, we are building a biological crop-protection platform based on targeted, non-living protein complexes. Our technology combines AI-guided protein design, insect genetics and microbial production. We are moving active prototypes from biological testing into scalable fermentation, formulation, soil and field validation.

The role

We are looking for a hands-on, mid-level Bioprocessing Specialist to turn benchtop microbial fermentation into repeatable pilot production, support transfer to manufacturing partners and deliver consistent material for formulation, soil and field testing. This individual-contributor role suits someone who has directly participated in one or two scale-up or technology-transfer cycles and still enjoys working at the bench and bioreactor.

Key responsibilities

• Fermentation development. Plan and execute microbial batch and fed-batch fermentations, including media, feed, induction, pH, dissolved oxygen, aeration, temperature and harvest strategies.
• Protein expression and optimization. Improve recombinant protein expression, solubility, yield, product quality and robustness by linking process conditions to biological performance.
• Scale-up and technology transfer. Translate laboratory processes toward 50-1,000 L and beyond; define scale criteria, run plans, acceptance criteria and transfer packages, and support partner execution.
• Production execution. Run repeatable, traceable batches that supply characterized material for formulation, soil, greenhouse and field testing.
• Harvest and fit-for-purpose recovery. Personally perform and improve harvest, cell disruption or extraction, clarification, concentration and the minimal purification needed for testing.
• Troubleshooting, data and quality control. Use structured experiments, data analysis, in-process controls and practical quality checks to investigate deviations and connect upstream choices to recovery and lot quality.
• Documentation and collaboration. Maintain SOPs, batch records, risk assessments and transfer documentation, and work closely with scientists, formulation and agronomy colleagues, quality functions and external manufacturing partners.

You will be responsible for practical process development and execution while helping Yngvi Bio build the documentation and production discipline needed for reliable internal batches and partner transfer.

Qualifications

• Relevant experience. Typically 3-6 years in microbial fermentation, upstream bioprocess development or production-facing biotechnology.
• Hands-on fermentation. Strong practical experience setting up, running, sampling and troubleshooting microbial bioreactors.
• Recombinant protein expression. Practical experience with microbial expression is important; bacterial systems such as E. coli are preferred. You can connect process conditions to expression, solubility, quality and recovery.
• Scale-up evidence. Direct involvement in one or two scale-up or technology-transfer cycles beyond small laboratory reactors, with the ability to explain what changed between scales.
• Production and downstream practice. Experience producing test or pilot material and personally performing harvest, extraction, clarification and basic purification or recovery.
• Education and working style. BSc, MSc, PhD or equivalent practical expertise in engineering, biotechnology, microbiology, biochemistry or a related field, combined with a hands-on, solution-oriented approach suited to an early-stage company.
• Valuable extras. Experience expressing virus-like particles, capsid-like structures, multimeric or self-assembling proteins, or other complex recombinant proteins is a bonus. Experience with design of experiments, automation, advanced downstream processing, CDMOs or agricultural biotechnology is also valuable.

What we offer

• A role with direct influence on how Yngvi Bio turns designed proteins into repeatable, scalable production.
• Work spanning fermentation, production, scale-up and the delivery of material for formulation, soil and field testing.
• A small international team at BioInnovation Institute where you can build practical systems, solve difficult technical challenges and grow with the role.

Role details

Location: BioInnovation Institute, Copenhagen. The role is laboratory-based and may involve occasional partner or manufacturing-site travel.

Start date: As soon as possible, by agreement.