Postdoctoral Research Associate - Infectious Diseases

Washington University in St. Louis; Berlin; Vor Ort; EUR 47.000 - 60.000; Vollzeit

Zusammenfassung

Washington University in St. Louis invites applications for a Postdoctoral Research Associate in the Kotov lab to study innate immunity during Mycobacterium tuberculosis infection using mouse models in a BSL3 facility.

The successful candidate will lead projects, work primarily in wet labs with dry lab components, and may perform single-cell RNA-seq data analyses while collaborating across the lab and with external groups.

Qualifikationen

• Ph.D., M.D. or equivalent terminal degree.
• No specific certifications required.
• No specific work experience required.
• Experience with mice, flow cytometry, and microscopy encouraged.
• Experience analyzing transcriptomic data is a plus.

Aufgaben

• Use flow cytometry, microscopy, bulk and single-cell RNA-sequencing to study host response to Mtb infection in mouse models.
• Perform basic bioinformatics analysis of scRNA-seq and spatial transcriptomic datasets.
• Mentor undergraduates, technicians, and rotating graduate students.
• Collaborate with researchers inside and outside Washington University in St. Louis.
• Present at national and international conferences and write manuscripts.
• Lead one or two projects independently.

Kenntnisse

Flow cytometry

Microscopy

Single-cell RNA-seq

Spatial transcriptomics

Bioinformatics

Mentoring

Ausbildung

PhD/MD

Tools

RNA-seq analysis pipelines

Mouse models

BSL3 facility

Jobbeschreibung

Location

SAINT LOUIS, MO 63110

Position Summary

In support of a recently funded NIH DP2 award, we are looking for a cellular immunologist to join the Kotov lab as a Postdoctoral Research Associate. We focus on the innate immune response to Mycobacterium tuberculosis (Mtb) infection as it is the leading cause of death from a single pathogen worldwide. Our goal is to understand the host response to this infection to identify novel targets for host-directed therapies.

There are a number of projects available, all of which focus on the host response during Mtb infection, with a primary focus on plasmacytoid dendritic cells, macrophages, and neutrophils.

The ideal candidate will be motivated, independent, and collegial, with the expectation that they will lead a project or two. This position is primarily a wet lab position (though has dry lab components!) involving the use of mouse models in an animal BSL3 facility. Previous BSL3 experience is not a requirement. Candidates with experience with mice, flow cytometry, and microscopy are encouraged to apply. Additionally, previous experience analyzing transcriptomic data is an advantage, as the dry lab (e.g., single cell RNA-sequencing dataset analysis) informs the wet lab work.

Job Description

Primary Duties & Responsibilities:

For more information about the Kotov lab, please visit https://kotovlab.wustl.edu/.

Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/.

Trains under the supervision of a faculty mentor including (but not limited to):

• Leverage cellular immunology techniques (flow cytometry, microscopy, bulk and single cell RNA-sequencing, spatial transcriptomics) to study the host response against Mtb infection using mouse models in a BSL3 facility.
• Perform basic bioinformatics analysis of single cell RNA-sequencing and spatial transcriptomic datasets.
• Mentor undergraduates, research technicians, and rotating graduate students.
• Collaborate with researchers inside and outside of Washington University in St. Louis.
• Present at national and international conferences.
• Write manuscripts.

Working Conditions:

This position works in a laboratory environment with potential exposure to biological and chemical hazards.The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range:

Base pay is commensurate with experience.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education:

Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.

Certifications** /Professional Licenses **:

No specific certification/professional license is required for this position.

Work Experience:

No specific work experience is required for this position.

Skills:

Not Applicable

Driver’s License:

A driver’s license is not required for this position.

More About This Job

At WashU, postdoctoral appointments:

• Have a 5-year term limit that includes previous experience.

Preferred Qualifications

Education:

No additional education unless stated elsewhere in the job posting.

Certifications** /Professional Licenses **:

No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience:

No additional work experience unless stated elsewhere in the job posting.

Skills:

Collaboration, Data Analysis, Data Interpretations, Experimentation, Laboratory Operations, Laboratory Techniques, Researching, Results Reporting, Scientific Writing

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.