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Mercor seeks a Computational Pharmacokinetics & Systems Biology Expert to design graduate-level problems that use real scientific software for research-level simulations and analyses. You will craft challenging, multi-step workflows and test them against cutting-edge AI models, refining them for the target difficulty.
You will work with libRoadRunner, Tellurium, or SBML-based tools, applying your graduate training to build and validate experiments, with emphasis on reproducibility and thoughtful
We're building a large-scale benchmark to test how well advanced AI systems can solve hard scientific and engineering problems. As a task designer, you'll create challenging computational problems that check whether AI can use real scientific software to do research-level work — running simulations, interpreting results, designing experiments, and uncovering hidden information from data.
This isn't a typical data-labeling job. You'll design original, graduate-level problems based on real scientific workflows, test them against cutting-edge AI models, and fine-tune them until the difficulty is just right.
You'll create problems that require skilled use of specialized scientific software. Some will ask the AI to compute exact answers from a fully defined setup — testing whether it can correctly carry out complex, multi-step workflows. Others will be harder: the AI must plan a series of queries or experiments to uncover information that isn't directly visible, which means thinking strategically about what to measure, how to read partial results, and how to narrow down the possibilities efficiently.
Each problem goes through a testing loop against state-of-the-art AI models, and you'll refine it until it hits the target difficulty.
We're especially interested in experts with deep, hands-on experience in:
— working with libRoadRunner, Tellurium, or SBML-based tools for compartmental PK/PD modeling, enzyme kinetics, or systems biology simulations.
Experience with other specialized software in this domain will also be considered.
You have graduate-level expertise (MS or PhD preferred) in the domain above, with real hands-on experience using these tools — not just theoretical knowledge. You've written code using these libraries to solve actual research problems, and you understand where they break, what their edge cases are, and what makes a problem genuinely hard rather than just complicated.
Beyond domain expertise, the best candidates think like puzzle designers: building problems where the challenge comes from smart reasoning rather than raw computation, where several approaches seem plausible but only careful analysis reveals the right one, and where surface-level pattern matching won't get you to the answer.