Technical Development Leader

F. Hoffmann-La Roche AG; Basel; Vor Ort; CHF 180.000 - 240.000; Vollzeit

Zusammenfassung

Roche Basel seeks a Technical Development Leader (TDL) to guide CMC strategy for clinical candidates and to drive development from early trials to launch. You will lead Technical Development Teams and coordinate with global cross-functional partners to ensure scientific integrity and proactive risk management.

The role requires senior expertise in CMC, strategic program leadership, and the ability to influence executives while managing budgets and timelines across a complex portfolio.

Qualifikationen

• 7–15 years in the pharmaceutical industry with CMC leadership or deep molecule process/formulation expertise.
• Strategic & program leadership across the full drug development lifecycle.
• Excellent verbal and written communication with ability to influence senior management.

Aufgaben

• Lead scientific and technical teams to design multifaceted CMC strategies for regulatory approval and commercial success.
• Serve as primary liaison to asset teams, senior management, and governance committees.
• Oversee end-to-end CMC development including resource forecasting and milestone tracking.
• Drive informed investment decisions and proactive risk mitigation with contingency plans.

Kenntnisse

CMC leadership

Strategic leadership

Cross-functional leadership

Communication

Ausbildung

BS/MS/PhD in Chemistry, Pharmaceutics, Chemical Engineering or related discipline

Jobbeschreibung

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position At Roche, we advance science so that we all have more time with the people we love. Located at our Basel site, the Technical Development Leader (TDL) plays a pivotal role in bringing innovative medicines to life. In this strategic leadership role, you will lead Technical Development Teams (TDTs) to design and drive Chemistry, Manufacturing, and Control (CMC) strategies for clinical drug candidates for synthetic molecules. From early human trials through product launch, you will ensure scientific integrity, proactive risk mitigation, and seamless collaboration across global cross-functional teams.

The Opportunity

As a TDL, you will be accountable for the end-to-end technical strategy and execution of complex pharmaceutical assets:

• Strategic Leadership: Lead scientific and technical teams throughout the product lifecycle, designing multifaceted CMC strategies (manufacturing, formulation, supply chain) for regulatory approval and commercial success.
• Governance & Influence: Serve as the primary liaison to asset teams, senior management, and governance committees, delivering transparent updates to drive enterprise-wide decisions.
• Operational & Financial Stewardship: Oversee end-to‑end CMC development, including resource forecasting, financial stewardship, and milestone tracking for flawless execution.
• Risk & Decision Management: Drive informed investment decisions and proactive risk mitigation, establishing robust contingency plans for critical project milestones.

Who You Are

You are a recognized thought leader in CMC and product development with a passion for transforming science into life‑saving therapies. You combine deep technical expertise with strategic vision and strong executive presence.

Education

• B.S., M.S., or Ph.D. in Chemistry, Pharmaceutics, Chemical Engineering, or a related technical discipline.

Professional Experience

• 7-15 years in the pharmaceutical industry, with proven experience as a CMC team leader or deep expertise in synthetic molecule process and formulation development.
• Strategic & Program Leadership: Broad understanding of the full drug development lifecycle, with a track record of managing complex, cross‑functional programs.
• Communication & Negotiation: Exceptional communication skills with a proven ability to influence senior management and external partners.
• Mobility: Willingness to travel nationally and internationally (approx. 5-10%).

Are you ready to make a difference for our patients?

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life‑changing healthcare solutions that make a global impact. Let's build a healthier future, together.

Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now - even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.