Spatial / Single Cell Genomics Expert

Eidgenössische Technische Hochschule Zürich; Basel; Vor Ort; CHF 80.000 - 100.000; Vollzeit

Benefits dieser Stelle

Attractive employment conditions

Opportunities for professional development

Access to state-of-the-art instrumentation

Zusammenfassung

Eidgenössische Technische Hochschule Zürich in Basel is seeking a highly motivated PhD-level Application Scientist to enhance R&D and user support in genomics. Candidates should hold a relevant PhD and possess strong hands-on experience in next-generation sequencing, single-cell genomics, and more.

This role offers interaction with a diverse research community and access to advanced genomics technologies. The workplace promotes diversity and sustainability as core values.

Qualifikationen

• PhD in a relevant life science discipline.
• Strong hands-on experience with modern genomics techniques.
• Excellent organizational, analytical, and problem-solving skills.

Aufgaben

• Evaluate and implement emerging genomics technologies.
• Support user projects through experimental design and troubleshooting.
• Develop novel workflows with a focus on scalability and robustness.
• Participate in internal R&D projects and technology pilots.

Kenntnisse

Hands-on experience with modern genomics and molecular biology techniques

Next-generation sequencing

Single-cell genomics

Spatial transcriptomics

Multi-omics workflows

High-throughput library preparation methods

Ausbildung

PhD in biology, molecular biology, genomics, bioengineering, or related life science discipline

Jobbeschreibung

The Genomics Facility Basel (GFB) is a central academic technology platform jointly operated by the University of Basel and the Department of Biosystems Science and Engineering (D‑BSSE) of ETH Zurich. The facility supports cutting‑edge life science research across campus boundaries and provides services and expertise to associated institutions, including the Botnar Institute of Immune Engineering (BIIE), as well as external academic and industrial partners.

Project background

GFB offers access to state‑of‑the‑art genomics technologies and actively drives innovation in next‑generation sequencing, single‑cell and spatial genomics, and emerging multi‑omics approaches. To strengthen our R&D and user support activities, we are seeking a highly motivated PhD‑level Application Scientist to join our team.

• Evaluation, implementation, and benchmarking of emerging genomics technologies within an academic core facility environment
• Scientific and technical support of user projects, including experimental design, method selection, and troubleshooting, in close collaboration with researchers from the University of Basel, ETH Zurich, and associated institutes
• Research and development of novel workflows, with a strong focus on establishing scalable, robust, and high‑throughput approaches in:
  • Library preparation technologies
  • Single‑cell sequencing
  • Spatial transcriptomics
  • Multi‑omics strategies
• Optimization, validation, and documentation of methods and standard operating procedures (SOPs)
• Active participation in internal R&D projects, technology pilots, and collaborative research initiatives
• Communication of new technologies and results through user consultations, training sessions, presentations, and written documentation

Profile

• PhD in biology, molecular biology, genomics, bioengineering, or a related life science discipline
• Strong hands‑on experience with modern genomics and molecular biology techniques, particularly next‑generation sequencing.
• Demonstrated experience in one or more of the following areas:
  • Single‑cell genomics
  • Spatial transcriptomics
  • Multi‑omics workflows
  • High‑throughput library preparation methods
• A strong academic mindset with curiosity for technology development and method optimization
• Ability to work independently while contributing effectively within a collaborative, service‑oriented academic environment
• Committed to excellence within a collaborative team, focusing on shared success and high‑quality service delivery in an academic setting
• Excellent organizational, analytical, and problem‑solving skills
• Practical experience in working in an NGS core facility is an advantage.
• Fluent oral and written communication skills in English are essential

Workplace

Environment: Basel, a major international hub for life sciences and biomedical research.

We offer

• An intellectually stimulating position within a leading academic technology platform at the interface of research, service, and innovation
• The opportunity to actively shape and establish new genomics technologies and workflows
• Daily interaction with a diverse and highly interdisciplinary research community
• Access to state‑of‑the‑art instrumentation and evolving genomics platforms
• Attractive employment conditions and opportunities for professional development
• A workplace in Basel, a major international hub for life sciences and biomedical research

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Sustainability is a core value for us – we are consistently working towards a climate‑neutral future.

Questions regarding the position should be directed to Dr. Christian Beisel: [e-mail].