Spatial / Single Cell Genomics Expert

Master in Integrated Building Systems ETH Zürich; Basel; Vor Ort; CHF 110.000 - 150.000; Vollzeit

Zusammenfassung

Genomics Facility Basel (GFB) jointly operated by the University of Basel and ETH Zurich invites applications for a PhD-level Application Scientist. The role spans evaluation of cutting-edge genomics technologies, design of experiments, and development of scalable workflows in single-cell, spatial transcriptomics, and multi-omics.

You will support researchers from Basel, ETH Zurich and partner institutes, contribute to SOPs, and communicate findings through training and documentation.

Qualifikationen

• PhD in biology, molecular biology, genomics, bioengineering, or a related life science discipline.
• Strong hands-on experience with modern genomics techniques, particularly next-generation sequencing.
• Experience in one or more: single-cell genomics, spatial transcriptomics, multi-omics workflows, high-throughput library preparation methods.
• Academic mindset with curiosity for technology development and method optimization.
• Ability to work independently while contributing within a collaborative academic environment.
• Committed to excellence in a collaborative team and high-quality service delivery in academia.
• Excellent organizational, analytical, and problem-solving skills.
• Fluent oral and written English.

Aufgaben

• Evaluate, implement, and benchmark emerging genomics technologies in an academic core facility.
• Provide scientific and technical support for user projects, including experimental design and troubleshooting.
• Develop novel workflows focusing on scalable, high-throughput approaches in library prep, single-cell sequencing, spatial transcriptomics, and multi-omics.
• Optimize, validate, and document methods and SOPs.
• Participate in internal R&D projects, tech pilots, and collaborative initiatives.
• Communicate results through user consultations, training sessions, and written documentation.

Kenntnisse

Genomics techniques

Next-generation sequencing

Single-cell sequencing

Spatial transcriptomics

Multi-omics

SOP development

Ausbildung

PhD in biology or related life science

Tools

NGS platforms

Jobbeschreibung

100%, Basel, fixed-term

The Genomics Facility Basel (GFB) is a central academic technology platform jointly operated by the University of Basel and the Department of Biosystems Science and Engineering (D-BSSE) of ETH Zurich. The facility supports cutting-edge life science research across campus boundaries and provides services and expertise to associated institutions, including the Botnar Institute of Immune Engineering (BIIE), as well as external academic and industrial partners.

Project background

GFB offers access to state-of-the-art genomics technologies and actively drives innovation in next-generation sequencing, single-cell and spatial genomics, and emerging multi-omics approaches. To strengthen our R&D and user support activities, we are seeking a highly motivated PhD-level Application Scientist to join our team.

Job Description

• Evaluation, implementation, and benchmarking of emerging genomics technologies within an academic core facility environment
• Scientific and technical support of user projects, including experimental design, method selection, and troubleshooting, in close collaboration with researchers from the University of Basel, ETH Zurich, and associated institutes
• Research and development of novel workflows, with a strong focus on establishing scalable, robust, and high-throughput approaches in:
  • Library preparation technologies
  • Single-cell sequencing
  • Spatial transcriptomics
  • Multi-omics strategies
• Optimization, validation, and documentation of methods and standard operating procedures (SOPs)
• Active participation in internal R&D projects, technology pilots, and collaborative research initiatives
• Communication of new technologies and results through user consultations, training sessions, presentations, and written documentation

Profile

• PhD in biology, molecular biology, genomics, bioengineering, or a related life science discipline
• Strong hands-on experience with modern genomics and molecular biology techniques, particularly next-generation sequencing.
• Demonstrated experience in one or more of the following areas:
  • Single-cell genomics
  • Spatial transcriptomics
  • Multi-omics workflows
  • High-throughput library preparation methods
• A strong academic mindset with curiosity for technology development and method optimization
• Ability to work independently while contributing effectively within a collaborative, service-oriented academic environment
• Committed to excellence within a collaborative team, focusing on shared success and high-quality service delivery in an academic setting
• Excellent organizational, analytical, and problem-solving skills
• Practical experience in working in an NGS core facility is an advantage.
• Fluent oral and written communication skills in English are essential

Workplace

We offer

• An intellectually stimulating position within a leading academic technology platform at the interface of research, service, and innovation
• The opportunity to actively shape and establish new genomics technologies and workflows
• Daily interaction with a diverse and highly interdisciplinary research community
• Access to state-of-the-art instrumentation and evolving genomics platforms
• Attractive employment conditions and opportunities for professional development
• A workplace in Basel, a major international hub for life sciences and biomedical research

Working, teaching and research at ETH Zurich

We value diversity and sustainability

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us - we are consistently working towards a climate-neutral future.

Curious? So are we.

Further information

Further information about the Genomics Facility Basel can be found on our website. Questions regarding the position should be directed to Dr. Christian Beisel: [e-mail] (no applications).

About ETH Zürich

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.