Senior Scientist, Mechanistic Pharmacology

CSL Behring AG; Schlieren; On-site; CHF 120,000 - 180,000; Full time

Job summary

CSL Behring AG in Schlieren, Switzerland, seeks a Senior Scientist, Mechanistic Pharmacology in Translational Research. You will develop and optimize advanced cellular models with translational relevance for cardiovascular and renal indications.

Lead the selection and use of model systems, design functional assays for target validation, and present data to project teams. A PhD plus 3+ years in industry or academia is preferred.

Qualifications

• PhD or equivalent in life sciences preferred.
• ≥3 years of relevant cardiovascular/renal biology experience.
• Expertise in complex cellular models and translationally relevant assays.

Responsibilities

• Develop, optimize, and apply advanced cellular models with translational relevance.
• Provide scientific leadership in model selection and use for projects.
• Design and execute functional assays for target validation and mechanistic studies.
• Communicate data clearly to teams and stakeholders.

Skills

Complex cellular models (iPSC, co-cult

Organoids/organ-on-a-chip

Translational pharmacology mindset

Scientific leadership

Data presentation to cross-functional

Education

PhD preferred

Postgraduate degree in life sciences

Job description

We are currently looking for a Senior Scientist, Mechanistic Pharmacology in Translational Research (complex in vitro models cardiovascular and renal indications) to join our team in Schlieren, ZH.

Key Tasks

• Develop, optimize, and apply advanced cellular and complex in vitro models with translational relevance for cardiovascular and renal indications
• Provide scientific leadership in the selection, establishment, and use of cellular model systems to support translational project objectives.
• Design and execute functional assays to generate high-quality data for target validation, mechanistic studies, and characterization of therapeutic candidates.
• Interact with project teams, communicating data, insights, and recommendations clearly to colleagues and stakeholders.
• Support external collaborations and outsourcing activities where needed, ensuring scientific quality and alignment with project goals.

Your Profile

• Postgraduate degree in Life Sciences, Pharmacology, Cell Biology, or a related scientific discipline; a PhD is preferred.
• At least 3 years of relevant experience in industry or a comparable academic research environment focused on cardiovascular or kidney biology
• Strong expertise in complex cellular model systems (ipsc, co-culture, organoids and/or organ-on-a-chip) and translationally relevant in vitro assay development.
• A problem-solving mindset with the ability to define critical scientific questions and translate them into effective experimental strategies.
• Demonstrated ability to present scientific data and concepts clearly to colleagues, cross-functional teams, and management.
• Strong interpersonal skills with the ability to collaborate effectively across internal teams and external partners.
• A proactive, hands-on, and solution-oriented approach, combined with a curious and disciplined mindset
• Strong collaborative mindset, with the flexibility to work effectively across teams and with different project stakeholders.