Senior Analytical Scientist (Biologics)

ALTEN; Vaud; Vor Ort; CHF 110.000 - 150.000; Vollzeit

Zusammenfassung

ALTEN is seeking a Senior Analytical Scientist to join a biologics-focused laboratory team, contributing to process improvement and manufacturing development in a GMP environment.

The role requires hands-on experience with HPLC/UHPLC, SEC, RP chromatography, ELISA, and strong data interpretation skills, with fluent English in a regulated setting.

Qualifikationen

• Degree in Biochemistry, Analytical Chemistry, Biotechnology, Pharmaceutical Sciences, or related field.
• Minimum 5 years of experience in pharmaceutical/biopharmaceutical industry.
• Hands-on with HPLC/UHPLC techniques and chromatography methods (SEC and Reverse Phase).
• Experience with ELISA and immunoassays.
• Experience analysing biologics, proteins or complex biomolecules.
• GMP-regulated environment experience.
• Fluent English (written and spoken).

Aufgaben

• Perform analytical testing of samples from manufacturing process improvement activities.
• Execute and troubleshoot LC methods including system setup, sample prep, data acquisition, interpretation.
• Conduct immunoassays and protein quantification analyses.
• Review, evaluate and statistically interpret analytical data.
• Compile results into technical reports and study summaries.
• Maintain accurate laboratory documentation and data integrity.
• Support instrument maintenance, qualification, calibration and troubleshooting.
• Investigate analytical anomalies and root causes.
• Participate in method development, qualification, optimization and transfer.
• Collaborate with cross-functional and international teams.

Kenntnisse

HPLC/UHPLC

SEC (Size Exclusion Chromatography)

Reverse Phase Chromatography

ELISA

GMP experience

Fluent English

Ausbildung

Master's degree in Biochemistry / Analytical Chemistry / Biotechnology

Tools

Chromeleon

Empower

JMP

LC-MS

Jobbeschreibung

We are supporting a leading international biopharmaceutical organization in the search for a Senior Analytical Scientist to join a laboratory-based team focused on biologics and process improvement activities.

This is an excellent opportunity for an experienced analytical scientist with a strong background in protein characterization, chromatography, and bioanalytical testing to contribute to innovative manufacturing and development projects within a highly regulated GMP environment.

Key Responsibilities

• Perform analytical testing of samples generated from manufacturing process improvement activities.
• Execute and troubleshoot liquid chromatography methods, including system setup, sample preparation, data acquisition, and interpretation.
• Conduct immunoassays and protein quantification analyses.
• Review, evaluate, and statistically interpret analytical data.
• Compile analytical results into technical reports and study summaries.
• Maintain accurate laboratory documentation and ensure data integrity compliance.
• Support analytical instrumentation maintenance, qualification, calibration, and troubleshooting activities.
• Investigate analytical anomalies and identify root causes.
• Participate in method development, qualification, optimization, and transfer activities.
• Collaborate with cross-functional and international teams to support project objectives.

Required Qualifications

• Degree in Biochemistry, Analytical Chemistry, Biotechnology, Pharmaceutical Sciences, or a related scientific discipline.
• Minimum 5 years of experience in the pharmaceutical or biopharmaceutical industry.
• Strong hands‑on experience with HPLC / UHPLC techniques.
• Expertise in chromatographic methods, particularly SEC (Size Exclusion Chromatography) and Reverse Phase Chromatography.
• Experience with ELISA and other immunoassay techniques.
• Experience analysing biologics, proteins, or other complex biomolecules.
• Strong data analysis and scientific interpretation skills.
• Experience working in GMP-regulated environments.
• Fluent English (written and spoken).

Nice to Have

• Experience with glycoproteins, glycosylation analysis, or protein characterization.
• Experience supporting process development or comparability studies.
• Knowledge of analytical method validation and lifecycle management.Experience with Chromeleon, Empower, JMP, or similar analytical software.
• Exposure to LC-MS or advanced biomolecule characterization techniques.

Personal Attributes

• Strong troubleshooting and problem‑solving skills.
• Scientific curiosity and analytical thinking.
• High attention to detail.
• Ability to work independently in a laboratory environment.
• Excellent communication and collaboration skills.
• Comfortable working in a fast-paced and dynamic project environment.