RiSM Internship for students in Pharmaceutical Sciences or Pharmaceutical Technology (Basel, 9-[...]

F. Hoffmann-La Roche AG; Basel; Vor Ort; CHF 20.088 - 26.784; Vollzeit

Zusammenfassung

A Roche Basel está oferecendo um estágio RiSM em Pharmaceutical & Solid State Development para estudantes universitários em Ciências Farmacêuticas ou Tecnologia Farmacêutica. O estágio envolve desenvolvimento de tecnologias de entrega de medicamentos, fabricação de dispersões amorfas e formação de formas sólido-fármaco.

O candidato ideal tem boa organização, trabalho em equipe, e conhecimentos de MS-Office, com proficiência em Inglês (Alemão é um diferencial).

Qualifikationen

• Estudante universitário (ou diplomando nos últimos 12 meses) em Ciências Farmacêuticas ou Tecnologia Farmacêutica.
• Interesse em formulação e fabricação de medicamentos.
• Conhecimento básico de MS-Office (Word, Excel, PowerPoint).
• Proficiente em Inglês; Alemão é um plus.

Aufgaben

• Apoiar o departamento Pharmaceutical & Solid State Development no desenvolvimento de tecnologias de entrega de fármacos.
• Revisar literatura relevante e seguir SOPs e equipamentos de fabricação/analítica.
• Fabricar e caracterizar dispersões sólidas amorfas para administração oral.
• Preparar e caracterizar formas farmacêuticas sólidas e discutir o progresso com os supervisores.

Kenntnisse

MS-Office

Inglês

Trabalho em equipe

Confiabilidade

Ausbildung

Estudante universitário (em Pharmaceutical Sciences ou Pharmaceutical Technology)

Tools

MS Office

Jobbeschreibung

## RiSM Internship for students in Pharmaceutical Sciences or Pharmaceutical Technology (Basel, 9-12 months)Candidatar-selocations: Baseltime type: Tempo integralposted on: Publicado hojejob requisition id: 202607-119050Na Roche, você pode-se apresentar como você mesmo, abraçado pelas qualidades únicas que traz. Nossa cultura incentiva a expressão pessoal, o diálogo aberto e as conexões genuínas, onde você é valorizado e respeitado por quem você é, e permitindo que você prospere tanto pessoal como profissionalmente. É assim que pretendemos prevenir, deter e curar doenças e garantir que todos tenham acesso aos cuidados de saúde hoje e nas gerações futuras. Junte-se à Roche, onde cada voz é importante.### A posição**Pharmaceutical & Solid State Development** is part of Pharma Technical Development and situated in Basel, Switzerland.Our key expertise is the development of robust and economic processes for drug substances with tailor-made solid state properties and patient centric formulations for the synthetic molecule portfolio of projects from early clinical studies to commercialization. We advance the design and delivery of transformative medicines by combining particle engineering, characterization, and formulation development - ensuring optimal drug performance, manufacturability, and patient-centric solutions from molecule to medicine.As an intern you will support the department **Pharmaceutical & Solid State Development** in the development of drug delivery technologies such as amorphous solid dispersions for oral delivery of bRo5 molecules.### The Opportunity● Review of the relevant literature applicable to the project● Training in relevant SOPs and manufacturing/analytical equipment● Manufacturing and characterization of spray dried amorphous solid dispersions● Preparation and characterization of solid dosage forms● Regular discussion of project progress with supervisors and planning of next steps● Writing of final report### Who you areYou are a **University student (or you graduated within 12 months prior to the start date) preferably in the subject of Pharmaceutical Sciences, Pharmaceutical Technology** or similar subjects and have an interest in formulation and manufacturing. Furthermore, you are interested in using and sharing your knowledge as part of your Internship in a modern working environment.Your further profile for this position:● Reliable and accurate working style in a non-GMP environment● Team-oriented and decision-making personality● Self-sufficient, problem solving-oriented work habits● Good knowledge of MS-Office (Word, Excel, PowerPoint)● Proficiency in English, German is a plusThis internship opportunity is one of a number of positions we offer in the department per semester and **is suitable for writing a Master/Diploma thesis**.The interviews will take place on an interview day with all considered candidates and representatives of the department.Your complete application includes the following documents:● A Current CV and a Motivation Letter● A certificate of enrollment (if you are currently studying)● For Non-EU/EFTA citizens: Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies and you must be enrolled during the entire duration of the internship● The RiSM task (see below)### Application process### The application deadline is **23.08.2026.** All successful final candidates will be invited to a virtual interview day which will take place on 14.10.2026.The Internship will start in October to December 2027 and has a duration of 9 to 12 months, please indicate your preferred start date in your application.More information about the Roche Internship program in Synthetic Molecules (RiSM) and other opportunities within this program you can find here.Are you ready to apply? We are looking for someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities.### Additional information (RISM Task)### Assume you are a formulation scientist that has the task to develop a poorly water soluble drug (MW 923.43 g/mol, LogP≈ 5.5 - 7.5. Solubility in DMSO: up to 100 mg/mL, Ethanol: up to ≈ 3-6 mg/mL) for the treatment of head-neck-cancer. What are your considerations with respect to the formulation, manufacturing technology and dosage form? Please use the information providedin the following article (Dana E. Moseson, Trong Bien Tran, Bharathi Karunakaran, Rohan Ambardekar, Tze Ning Hiew, Trends in amorphous solid dispersion drug products approved by the U.S. Food and Drug Administration between 2012 and 2023, International Journal of Pharmaceutics: X, Volume 7, 2024, 100259, https://doi.org/10.1016/j.ijpx.2024.100259.) toanswer those questions. We anticipate receiving your answers in the form of a slide deck suitable for presentation to a project team (maximum of 5 slides, PDF format) alongside your application.### Quem nós somosUm futuro mais saudável nos leva a inovar. Juntos, mais de 100 mil funcionários em todo o mundo se dedicam ao avanço da ciência, garantindo que todos tenham acesso à saúde hoje e nas próximas gerações. Nossos esforços resultam em mais de 26 milhões de pessoas tratadas com nossos medicamentos e mais de 30 bilhões de testes realizados usando nossos produtos de diagnóstico. Nós nos capacitamos para explorar novas possibilidades, promover a criatividade e manter as nossas ambições altas, para fornecer soluções de saúde que mudem a vida e causem um impacto global.Vamos construir juntos um futuro mais saudável.**A Roche é um empregador que pratica políticas de igualdade de oportunidades.**