PhD: Nanozyme Coatings for Antimicrobial Implants

EMPA - Eidgenössische Materialprüfungs- und Forschungsanstalt; Dübendorf; Vor Ort; CHF 39.000 - 54.000; Vollzeit

Zusammenfassung

Empa, a Swiss research institution and ETH Domain member, offers a three-year PhD position in the Nanomaterials in Health Lab to develop stimuli-responsive nanozyme coatings for personalized medical implants. The project is part of the Marie Skłodowska-Curie Doctoral Network Implant-to-Market (i2M), linking materials science, biology and regulatory science. The candidate will work at Empa St.

Gallen with joint affiliation to ETH Zürich (D-HEST, Prof. Peter Wick) under Dr. Giacomo Reina.

Qualifikationen

• Master's degree in biomaterials, chemistry, nanotechnology, or biomedical engineering.
• Experience in nanomaterial synthesis and characterization.
• Familiarity with cell culture and in vitro assays.
• Experience in catalysis, programming and large data analysis is a plus.

Aufgaben

• Design and synthesize nanozymes: Develop nanozymes, and optimize their physicochemical and catalytic properties.
• Develop functional implant coatings: Establish reproducible strategies for integrating nanozymes onto implant surfaces and investigate their compatibility with different implant architectures and surface modifications.
• Evaluate antimicrobial activity: Investigate the ability of nanozyme-coated surfaces to inhibit bacterial growth and biofilm formation while reducing reliance on conventional antibiotics.
• Investigate nano-bio interactions: Study cellular responses to nanozyme-coated implants, including cytocompatibility, macrophage activation, cytokine production and parameters related to osteointegration.
• Study stability, ageing and biodegradation: Investigate the transformation of low-dimensional nanozyme coatings in biologically relevant fluids.

Kenntnisse

Nanomaterial synthesis

Characterization

Cell culture

In vitro assays

Programming

Data analysis

Ausbildung

Master's degree in biomaterials, chemistry, nanotechnology, or biomedical engineering

Jobbeschreibung

Empa, a Swiss research institution and ETH Domain member, offers a three-year PhD position in the Nanomaterials in Health Lab to develop stimuli-responsive nanozyme coatings for personalized medical implants. The project is part of the Marie Skłodowska-Curie Doctoral Network Implant-to-Market (i2M), linking materials science, biology and regulatory science. The candidate will work at Empa St.

Gallen with joint affiliation to ETH Zürich (D-HEST, Prof. Peter Wick) under Dr. Giacomo Reina.