PhD in Skin Immunology: Metabolic T Cell Research

Job-Room; Bern; Vor Ort; CHF 60.000 - 80.000; Vollzeit

Zusammenfassung

The laboratory of Prof. Christoph Schlapbach at Inselspital Bern and the University of Bern invites applications for a PhD project in human skin immunology.

The successful candidate will define how metabolic pathways regulate skin-resident memory TH cells and explore metabolic reprogramming as a route to durable disease control, using immunology, multi-omics and ex vivo skin models. The position is a 4-year, full‑time, temporary contract with enrollment in the Graduate School for Cellular and

Qualifikationen

• A degree in natural sciences (MSc) acceptable for matriculation at a Swiss University.
• Fluency in English (oral and written).
• Dedication to science and academia.
• Theoretical & practical skills in immunology, molecular & cellular biology.
• Academic excellence, a professional work attitude, and a proactive and self-driven work ethic.
• Enthusiastic and highly motivated.

Aufgaben

• Isolation and functional characterization of human memory T-cell subsets.
• Multi-parameter flow cytometry and fluorescence-activated cell sorting.
• CRISPR/Cas9 genome editing and RNA interference.
• Metabolic phenotyping using seahorse extracellular flux analysis.
• Bulk, single-cell and spatial transcriptomics.
• Human skin explant skin culture models.
• Immunofluorescence and Immunohistochemistry.
• Bioinformatic analysis of transcriptomic datasets.
• Supervise Master’s students and present research at conferences.

Jobbeschreibung

The laboratory of Prof. Christoph Schlapbach at Inselspital Bern and the University of Bern invites applications for a PhD project in human skin immunology.

The successful candidate will define how metabolic pathways regulate skin-resident memory TH cells and explore metabolic reprogramming as a route to durable disease control, using immunology, multi-omics and ex vivo skin models. The position is a 4-year, full‑time, temporary contract with enrollment in the Graduate School for Cellular and