PhD Biomedical Materials: Enzyme-Responsive Hydrogels

AO Foundation; Davos; Vor Ort; CHF 42.000 - 62.000; Vollzeit

Benefits dieser Stelle

Social benefits incl. vacation days &

Flexible hours & location

Internal skills training

Zusammenfassung

AO Foundation in Davos Platz (GR) invites applications for a PhD Student in Biomedical Materials within the PREPARE project. The PhD student will work under AO Research Institute Davos and in collaboration with the University of Fribourg, focusing on enzyme-responsive hydrogels and immunomodulator delivery to advance localized infection prevention.

The role requires a Master’s degree in a relevant field and excellent English, with duties spanning materials synthesis, characterization, and

Qualifikationen

• Master's degree in pharmaceutical sciences, chemistry, biomaterials science/engineering or related discipline.
• Excellent communication skills in English.
• Ability to design, plan, and execute experimental studies independently.
• Strong interest in biomaterials science, innate immunity, and translational research.

Aufgaben

• Develop a hydrogel responsive to degrading enzymes for on demand release and characterize gels by NMR, FT-IR and rheology.
• Incorporate small molecule immunomodulators into the hydrogel with covalent tethering or encapsulation.
• Engineer enzyme-triggered release systems using core-shell particles for controlled delivery.
• Evaluate neutrophil-related hydrogel degradation and release kinetics using in vitro assays.

Kenntnisse

English communication

Independent experimental design

Interdisciplinary collaboration

Biomaterials interest

Analytical thinking

Ausbildung

Master's degree in pharmaceutical sciences, chemistry, biomaterials science/engineering or related discipline

Tools

NMR

FT-IR

Rheology

UV spectroscopy

HPLC

Jobbeschreibung

AO Foundation in Davos Platz (GR) invites applications for a PhD Student in Biomedical Materials within the PREPARE project. The PhD student will work under AO Research Institute Davos and in collaboration with the University of Fribourg, focusing on enzyme-responsive hydrogels and immunomodulator delivery to advance localized infection prevention.

The role requires a Master’s degree in a relevant field and excellent English, with duties spanning materials synthesis, characterization, and