Lifecycle Leader - Ophthalmology

F. Hoffmann-La Roche AG; Basel; On-site; CHF 250,000 - 360,000; Full time

Job summary

Roche is seeking a Lifecycle Leader to drive asset strategy from research to patient, coordinating with global teams to maximize value and ensure patient access. You will lead cross-functional efforts across development, strategy, and commercial teams, embodying the OnePharma approach.

The role emphasizes end-to-end lifecycle execution, alignment with business objectives, and delivering evidence-driven value. Basel-based role with global impact and leadership responsibility.

Qualifications

• Bachelor’s degree required in marketing, business, life sciences or related field.
• Experience developing and overseeing breakthrough development or commercial strategies with strong launch experience.
• Strategic leadership with ability to influence cross-functional teams and drive long-term vision.

Responsibilities

• Develop and shape long-term asset strategy in partnership with development and strategy leads.
• Lead integrated cross-functional decision-making to maximize asset value across lifecycle.
• Deliver lifecycle value by guiding indications, formulations, devices, diagnostics and digital tools with evidence strategy.

Skills

Strategic Leadership

Global Leadership

Cross-functional collaboration

Portfolio management

Synthesis & strategic clarity

Education

Bachelor’s Degree

MD/PhD or MBA (additional)

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Roche - we advance science so that we all have more time with the people we love

Our Global Pharma Strategy (GPS) team plays a pivotal role in shaping the future of healthcare by driving the strategic direction of our innovative product portfolio. As a member of the GPS team, you will be at the forefront of transforming groundbreaking scientific discoveries into accessible and impactful healthcare solutions for patients worldwide. We are seeking a dynamic and visionary professional who thrives in a collaborative environment and is passionate about making a difference

The Opportunity

As a Lifecycle Leader you will lead the asset(s) strategy and portfolio from research through to the patient. You will play a critical role acting as single accountable to Late Stage Portfolio Committee (LSPC), maximizing the value of a product for patients, society, and the company by leading an integrated, global and cross-functional strategy and team.

Key Responsibilities

1. Strategy & Vision (Shaping the Long-Term Path)

• Shaping the long-term vision and strategy for one or several asset programs—which can be large and/or complex—in partnership with early development, Pharma Development, Global Pharma Strategy, Pharma Development Medical Affairs leads, and respective external partners.

• Unlock value earlier: Being involved earlier in the lifecycle to create a seamless transition from early to late stage (e.g., providing relevant input into the one asset team at critical time points such as a pivotal enabling Clinical Development Plan (CDP)).

• Supporting relevant early development asset teams, licensing, and other business development activities.

1. Integrated Leadership & Decision making (Driving Cross-Functional Success)

• Driving alignment and integrated decision-making with the Global Development Team, Global Technical Team and Commercial Leadership Team to realize the potential of the asset(s), within the context of the asset, disease area and therapeutic area strategies.

• Accountability to drive asset/disease area & enterprise mindset and team capability development (in line with OnePharmaStrategy).

• Serving as an inspiring leader, aligning people towards a vision while building a culture of accountability, collaboration, inclusion, and trust.

• Serving as a thought partner and sounding board for the GPS and cross organisation teams and relevant internal and external stakeholders, ensuring that franchise and enterprise goals are met.

1. Lifecycle Value & Execution (Maximizing Value and Delivery)

• Accountable for the resource ask, appropriate utilization, and the delivery of the aNPV (Adjusted Net Present Value) to the Late Stage Portfolio Committee (LSPC).

• Lifecycle excellence: Continually assess and evolve the asset strategy, in the context of external dynamics, new opportunities and DA strategy, by evaluating and triggering different value levers to maximise the asset's potential.

• This includes the integrated leadership to propose and deliver indications, formulations, devices, diagnostics and digital tools, along with the evidence generation strategy, to address the appropriate treatable population in collaboration with the Commercial Leadership Team (CLT), Global Development Team (GDT), Global Technical Team (TDT) and others.

Who You Are

• Educational Background: A Bachelor's Degree is required, preferably in a marketing, business management, or life sciences discipline. MD, PhD, or other relevant Graduate, Postgraduate Degree or MBA (depending on the Lifecycle of the product) is an additional plus.

• Substantial Pharma Experience: Demonstrable previous accomplishments should include developing and overseeing the execution of breakthrough development and/or commercial strategies that led to considerable financial results. Equally important are product management and launch experience. An ability to quickly come up to speed and navigate technical, supply, development and regulatory challenges utilising a deep understanding of global health systems, access and reimbursement challenges. Therapeutic Area experience is preferred.

• Strategic & Global Leadership: The role requires outstanding leadership skills with a proven track record in building teams and the ability to influence in a cross-functional environment. You should have exceptional strategic orientation and agility, with an outstanding ability to develop a long‑term vision and a deep understanding of the global pharmaceutical/biotechnology industry to create robust and innovative business strategies.

• Synthesis & Strategic Ambiguity: Exceptional ability to synthesize and summarize key strategic concepts within ambiguity to deliver on key milestones, product targets, and maximum lifecycle value for patients, society, and the company.

• End-to-End & Portfolio Collaboration: Strong leadership skills and strategic agility with a proven ability to collaborate seamlessly End-to-End (E2E) across early to late stage development, as well as cross-functionally within the Ophthalmology portfolio and broader enterprise to drive shared disease area goals.

What success looks like in the role:

• Maximizing Value: Success is achieved by maximizing the product's lifecycle value to patients, society, and the company.

• Execution and Financial Targets: Ensuring the timely, on‑target, and within‑budget delivery of the product strategy, including meeting key milestones and financial targets for the product.

• Leadership and Accountability: A key measure of success is the ability to effectively develop and lead a high performing team to create and deliver the asset strategy within a dynamic internal and external context.

Join us in our mission to advance science and deliver hope to those who need it most.

Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.