Doctoral Researcher: Mechanobiology, Protein Engineering & ML

ETH Zürich; Basel; On-site; CHF 60,000 - 85,000; Full time

Benefits offered by this job

Doctoral program enrollment

Conference funding

Job summary

ETH Zürich’s Nash Lab in Basel seeks a Doctoral Student to develop high-throughput assays for protein interactions relevant to blood clotting and to apply sequencing data and ML to model mechanics. You will join two departments and work across experimental and computational biology, with hands-on training from design to predictive modeling.

The role includes collaboration with a DBSSE group, enrollment in the Basel doctoral program, and teaching involvement, all within an interdisciplinary,

Qualifications

• Master's degree in a relevant field.
• Strong quantitative background and interest in protein engineering.
• Experience with molecular biology and protein expression preferred.

Responsibilities

• Establish and validate high-throughput assay for protein interactions.
• Cross-validate assay results with AFM measurements.
• Design and construct DNA variant libraries; display on yeast.
• Apply sequencing to quantify phenotypes and develop ML models.
• Prepare data/manuscripts and present results; enroll in DBSSE Doctoral program.
• Contribute to undergraduate teaching and supervision.

Skills

Quantitative background

Python (ML data analysis)

English fluency

Team collaboration

Education

Master's degree in bioengineering, chemical engineering, biochemistry, molecular biology, biophysics

Tools

Yeast display

AFM

Next-generation sequencing

DNA variant libraries

Job description

ETH Zürich’s Nash Lab in Basel seeks a Doctoral Student to develop high-throughput assays for protein interactions relevant to blood clotting and to apply sequencing data and ML to model mechanics. You will join two departments and work across experimental and computational biology, with hands-on training from design to predictive modeling.

The role includes collaboration with a DBSSE group, enrollment in the Basel doctoral program, and teaching involvement, all within an interdisciplinary,